Gene
smad5
- ID
- ZDB-GENE-990603-9
- Name
- SMAD family member 5
- Symbol
- smad5 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Exhibits transcription regulatory region DNA binding activity. Involved in several processes, including embryonic morphogenesis; regulation of transcription, DNA-templated; and vasculature development. Predicted to localize to cytoplasm; nucleus; and transcription factor complex. Is expressed in eye and posterior lateral line primordium. Orthologous to human SMAD5 (SMAD family member 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 19 figures from 17 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- 49 figures from 28 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001132 | SMAD domain, Dwarfin-type |
| Domain | IPR003619 | MAD homology 1, Dwarfin-type |
| Domain | IPR013019 | MAD homology, MH1 |
| Family | IPR013790 | Dwarfin |
| Homologous_superfamily | IPR008984 | SMAD/FHA domain superfamily |
| Homologous_superfamily | IPR017855 | SMAD-like domain superfamily |
| Homologous_superfamily | IPR036578 | SMAD MH1 domain superfamily |
Domain Details Per Protein
| Protein | Length | Dwarfin | MAD homology 1, Dwarfin-type | MAD homology, MH1 | SMAD domain, Dwarfin-type | SMAD/FHA domain superfamily | SMAD-like domain superfamily | SMAD MH1 domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q9W7E7
|
464 | |||||||
|
UniProtKB:A5PMC0
|
464 |
Interactions and Pathways
Plasmids
No data available