| ZFIN ID: ZDB-GENE-990415-270 |
| Gene Name: | tumor protein p53 |
|---|---|
| Gene Symbol: | tp53 |
| Previous Names: | brp53, drp53, p53 (1), etID22686.5 (1), fb40d06, wu:fb40d06 (1), zgc:111919 |
| Nomenclature History | |
| All Expression Data: | 64 figures from 49 publications |
| Directly Submitted Expression Data: | 1 figure (1 image) from Thisse et al., 2004 [MGC:111919] |
| Wild-type Stages, Structures: | Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult) |
|---|---|
brain,
exocrine pancreas,
eye,
gill
|
|
| Curated Microarray Expression: | GEO (1) |
| Mutant lines: | 60 genotypes |
| Alleles: |
dzy7,
hu888,
la015599Tg,
la024884Tg,
la024885Tg
|
| Knockdown reagents: |
MO1-tp53,
MO3-tp53
(1),
MO4-tp53
(6),
MO5-tp53
(1),
MO6-tp53
(1)
|
| Data: | 9 figures from 7 publications |
| Observed in: |
apoptotic process,
eye,
gill,
gut
|
| Phenotype of Human Orthologue | OMIM Phenotype ID |
|---|---|
| Adrenal cortical carcinoma | 202300 |
| Breast cancer | 114480 |
| Choroid plexus papilloma | 260500 |
| Colorectal cancer | 114500 |
| Hepatocellular carcinoma | 114550 |
| Li-Fraumeni syndrome | 151623 |
| Nasopharyngeal carcinoma | 607107 |
| Osteosarcoma | 259500 |
| Pancreatic cancer | 260350 |
| {Basal cell carcinoma 7} | 614740 |
| {Glioma susceptibility 1} | 137800 |
| Ontology | GO Term |
|---|---|
| Biological Process | positive regulation of transcription, DNA-dependent (more) |
| Cellular Component | intracellular (more) |
| Molecular Function | protein binding (more) |
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|
|
|
| Type | Name | Length (bp) | Analysis | |
|---|---|---|---|---|
| mRNA | tp53-001 (1) | 2204 |
Select Tool
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| ncRNA | tp53-002 (1) | 802 |
Select Tool
|
|
| tp53-003 (1) | 579 |
Select Tool
|
||
| tp53-004 (1) | 748 |
Select Tool
|
| Tg(tp53-002:GFP) |
| tp53 Contained in: | [BAC] CH211-114C12 (1) (order this) |
| tp53 Encodes: |
[EST]
fb40d06 (1)
[cDNA] MGC:111919 (1) (order this) |
| Type | Accession # | Length (bp/aa) | Analysis |
|---|---|---|---|
| RNA | RefSeq:NM_001271820 (1) | 2236 bp |
Select Tool
|
| Genomic | GenBank:AL928875 (1) | 158038 bp | |
| Polypeptide | UniProtKB:Q502Q9 (1) | 374 aa |
Select Tool
|
| Sequence Clusters | UniGene:75100 (1) |
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| Chr: 5 Details | View Map: Merged Individual Panels |
| Evidence | ||||||
|---|---|---|---|---|---|---|
| Species | Symbol | Chromosome (Position) | Accession # | AA | CL | SS |
| Zebrafish | tp53 | 5 |
|
|
|
|
| Human | TP53 | 17 (17p13.1) |
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| Mouse | Trp53 | 11 ( 42.83) |
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Request: 