ZFIN ID: ZDB-FISH-150901-16688
Fish name: tp53zdf1/zdf1
Genotype: tp53zdf1/zdf1
Targeting Reagent: none

HUMAN DISEASE MODELED by tp53zdf1/zdf1
No data available
GENE EXPRESSION
Gene expression in tp53zdf1/zdf1
Expressed Gene Structure Conditions Figures
apex1 whole organism control Fig. 6 from Pei et al., 2011
baxa whole organism standard conditions Fig. 4 with image from Chua et al., 2015
whole organism gamma ray Fig. 4 with image from Chua et al., 2015
bbc3 (not) whole organism standard conditions Fig. 4 with image from Chua et al., 2015
(not) whole organism gamma ray Fig. 4 with image from Chua et al., 2015
bnip3lb head, whole organism control Fig. 10 from Feng et al., 2011
head, whole organism hypoxia Fig. 10Fig. 11 from Feng et al., 2011
cdkn1a whole organism control Fig. 3 with image from Song et al., 2016
Fig. 4 with image from Chua et al., 2015
Fig. 4 with image from EspĂ­n et al., 2013
Fig. 5 with image from Santoriello et al., 2010
whole organism radiation Fig. 4 with image from Chua et al., 2015
Fig. 5 with image from Santoriello et al., 2010
creb1a whole organism control Fig. 6 from Pei et al., 2011
crestin cranial neural crest, neural crest, trunk neural crest (all 4) expand standard conditions Fig. 8 with image from Li et al., 2014
en2a midbrain hindbrain boundary control Fig. 2 with image from Dworkin et al., 2012
etv5b rhombomere central region control Fig. 1 with image from Terriente et al., 2012
fgf20a rhombomere neuron control Fig. 1 with imageFig. 2 with imageFig. 3 with imageFig. 4 with image from Terriente et al., 2012
gadd45aa whole organism control Fig. 3 with image from Song et al., 2016
her9 rhombomere compartment boundary control Fig. 2 with image from Terriente et al., 2012
hoxb1b neuroectoderm posterior region control Fig. 2 from Ma et al., 2015
mdm2 whole organism standard conditions Fig. 4 with image from Chua et al., 2015
Fig. 5 with image from Santoriello et al., 2010
whole organism radiation Fig. 4 with image from Chua et al., 2015
Fig. 5 with image from Santoriello et al., 2010
mpx myeloid cell control Fig. 2 from Bolli et al., 2010
myb hematopoietic multipotent progenitor cell, hematopoietic system posterior region, post-vent region hematopoietic stem cell standard conditions Fig. 6 with image from Wei et al., 2016
Fig. S13 with image from Jia et al., 2015
myl7 cardiac muscle cell standard conditions Fig. 4 from Yan et al., 2013
neurog1 neuroectoderm neuron control Fig. 5 with image from Terriente et al., 2012
pax2a midbrain hindbrain boundary control Fig. 2 with image from Dworkin et al., 2012
pes endoderm, eye, midbrain (all 4) expand control Fig. 7 with image from Provost et al., 2012
rag1 thymus T cell standard conditions Fig. 6 with image from Wei et al., 2016
rfng rhombomere compartment boundary control Fig. 1 with image from Terriente et al., 2012
rpl3 central nervous system, intestine, pharyngeal arch (all 5) expand control Fig. 5 with image from Provost et al., 2012
rrm2b whole organism control Fig. 3 with image from Song et al., 2016
sema3fb rhombomere compartment boundary, rhombomere 3, rhombomere 5 control Fig. 2 with image from Terriente et al., 2012
sema3gb rhombomere compartment boundary control Fig. 2 with image from Terriente et al., 2012
sox9b epiphysis, forebrain, immature eye (all 4) expand standard conditions Fig. 8 with image from Li et al., 2014
sox10 brain oligodendrocyte standard conditions Fig. 7 with image from Shin et al., 2012
tp53 (not) enteric circular muscle, eye neoplasm, (not) integument (all 8) expand standard conditions Fig. 4 with imageFig. 6 with imageFig. 7 with image from Chua et al., 2015
Fig. 7 with image from Heijnen et al., 2014
(not) whole organism gamma ray Fig. 4 with image from Chua et al., 2015
PHENOTYPE 
Phenotype in tp53zdf1/zdf1
Phenotype Conditions Figures
angiogenesis increased occurrence, abnormal standard conditions Fig. 5 with image from Kim et al., 2013
apoptotic process increased rate, abnormal hypoxia Fig. 12 from Feng et al., 2011
caudal fin apoptotic process increased process quality, abnormal chemical treatment: pharmaceutical Fig. 2 with image from Toruno et al., 2014
cellular response to ionizing radiation decreased process quality, abnormal radiation Fig. 2 with image from Toruno et al., 2014
double-strand break repair via homologous recombination increased frequency, abnormal standard conditions Fig. 1 from Gong et al., 2015
double-strand break repair via nonhomologous end joining increased frequency, abnormal standard conditions Fig. 1 from Gong et al., 2015
double-strand break repair via single-strand annealing increased frequency, abnormal standard conditions Fig. 1 from Gong et al., 2015
embryonic hemopoiesis process quality, normal control Fig. S7 with image from Novikov et al., 2013
heart morphology, normal control Fig. S7 with image from Novikov et al., 2013
heart tube decreased length, normal standard conditions Fig. 4 from Yan et al., 2013
neuron apoptotic process process quality, normal standard conditions Fig. 1 from Ko et al., 2011
nucleate erythrocyte normal amount, normal standard conditions Fig. 3 with image from Zhang et al., 2012
nucleate erythrocyte hemoglobin complex amount, normal control Fig. 1 with image from Narla et al., 2014
oocyte present, normal standard conditions Fig. 7 with image from Rodriguez-Mari et al., 2011
peripheral nervous system neoplastic, malignant, abnormal standard conditions Fig. 4 with image from Shive et al., 2010
peripheral nervous system neurofibrosarcoma increased amount, abnormal standard conditions Fig. 4 with image from Zhang et al., 2010
trunk sarcoma present, abnormal standard conditions Fig. 1 with image from Kim et al., 2013
whole organism morphology, normal control Fig. 2 with image from Dworkin et al., 2012
whole organism neoplastic, abnormal standard conditions Fig. 1 with image from Park et al., 2016
whole organism neoplasm increased occurrence, abnormal standard conditions Fig. 1 with image from Park et al., 2016

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