Li-Fraumeni syndrome

Term ID

DOID:3012

Synonyms

• LFS
• Li-Fraumeni Familiar cancer Susceptibility syndrome
• sarcoma, breast, leukaemia and adrenal gland syndrome
• SBLA syndrome

Definition

A syndrome characterized by autosomal dominant inheritance of increased risk of developing several types of cancer, including breast cancer, osteosarcomata and soft tissue sarcomata. (3)

References

• GARD:6902
• MESH:D016864
• NCI:C3476
• OMIM:PS151623
• ORDO:524
• SNOMEDCT_US_2023_03_01:428850001
• UMLS_CUI:C0085390

Ontology

Human Disease   ( DOID:3012 )