Gene

neurog1

ID
ZDB-GENE-990415-174
Name
neurogenin 1
Symbol
neurog1 Nomenclature History
Previous Names
  • neurod3
  • neurogenin1
  • neurogenin (1)
  • ngr1
  • cb260 (1)
  • chunp6899
  • neurogenic differentiation 3 (1)
  • ngn1
  • Zath4c (1)
  • zNgn1
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have E-box binding activity and chromatin binding activity. Involved in nervous system development; neuromast development; and olfactory placode development. Predicted to localize to nucleus. Is expressed in several structures, including ectoderm; nervous system; neural keel; neural plate; and neural tube. Orthologous to several human genes including NEUROG1 (neurogenin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
261 figures from 165 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
26 figures from 17 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With neurog1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Cranial dysinnervation disorder, congenital, with absent corneal reflex and developmental delay 620469
Associated With neurog1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Family IPR050359 Basic helix-loop-helix transcription factors
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Basic helix-loop-helix transcription factors Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain
UniProtKB:O42606 208
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA neurog1-201 (1) Ensembl 1,393 nt
Interactions and Pathways
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-neurog1 polyclonal Mouse
  • IHC
Abcam plc
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations