Gene

neurog1

ID
ZDB-GENE-990415-174
Name
neurogenin 1
Symbol
neurog1 Nomenclature History
Previous Names
  • neurod3
  • neurogenin1
  • neurogenin (1)
  • ngr1
  • cb260 (1)
  • chunp6899
  • neurogenic differentiation 3 (1)
  • ngn1
  • Zath4c (1)
  • zNgn1
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to enable E-box binding activity and chromatin binding activity. Involved in generation of neurons; hindbrain morphogenesis; and peripheral nervous system development. Acts upstream of or within several processes, including negative regulation of neurogenesis; nervous system development; and olfactory placode development. Predicted to be located in nucleus. Is expressed in several structures, including ectoderm; nervous system; neural keel; neural plate; and neural tube. Orthologous to human NEUROG1 (neurogenin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
247 figures from 158 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
26 figures from 17 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With neurog1 Human Ortholog
No data available
Associated With neurog1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Family IPR032653 Neurogenin-1
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain Neurogenin-1
UniProtKB:O42606 208
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-neurog1 polyclonal Mouse
  • IHC
Abcam plc
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations