ZFIN Gene: neurog1

ZFIN ID: ZDB-GENE-990415-174

ZFIN ID: ZDB-GENE-990415-174

Gene Name:

neurogenin 1

Gene Symbol:

neurog1

Sequence Ontology ID :

Previous Names:

neurod3, neurogenin1, neurogenin (1), ngr1, cb260 (1), chunp6899, neurogenic differentiation 3 (1), ngn1, Zath4c (1), zNgn1

Location:

Chr: 14 Mapping Details/Browsers

AUTOMATED DESCRIPTION

Predicted to have E-box binding activity and chromatin binding activity; involved in several processes, including animal organ development, nervous system development, and olfactory placode ...

GENE EXPRESSION
All Expression Data:	223 figures from 145 publications
Directly Submitted Expression Data:	6 figures (37 images) from Thisse et al., 2001 [cb260]
Wild-type Stages, Structures:	Blastula:Sphere (4.0h-4.33h) to Adult (90d-730d, breeding adult)
	alar plate midbrain region anterior lateral line ganglion anterior lateral line placode basal plate midbrain region brain neuroblast brain neuroblast (sensu Vertebrata) brain caudal tuberal nucleus caudal tuberculum dopaminergic neuron caudal tuberculum central nervous system cranial ganglion diencephalon dorsal region diencephalon ventral region diencephalon dorsal anterior lateral line ganglion dorsal root ganglion dorsal telencephalon dorsal thalamus posterior region dorsal thalamus ectoderm epibranchial placode epiphysis epithalamus facial ganglion facial placode forebrain neuroblast forebrain forebrain neural keel glossopharyngeal ganglion glossopharyngeal placode head hindbrain CNS neuron (sensu Vertebrata) hindbrain dorsal region hindbrain neuroblast hindbrain neuroblast (sensu Vertebrata) hindbrain rhombomere hindbrain hindbrain neural keel interneuron hindbrain neural keel sensory neuron hindbrain neural keel hindbrain neural plate hindbrain neural tube hypothalamus midbrain anterior region midbrain neuroblast (sensu Vertebrata) midbrain midbrain hindbrain boundary midbrain neural keel brain nucleus midbrain neural keel motor neuron Muller cell nucleus nervous system neural crest neural keel neural plate dorsal region neural plate neural rod neural tube neuroblast neuroectoderm neurogenic placode neuroblast neurogenic placode neuromast neuron neuronal stem cell optic stalk optic tectum otic epithelium otic placode otic vesicle epithelium otic vesicle neuroblast otic vesicle neuroblast (sensu Vertebrata) otic vesicle ventral region otic vesicle ventro-lateral region otic vesicle posterior lateral line placode presumptive brain presumptive diencephalon presumptive rhombomere 2 lateral region presumptive rhombomere 2 motor neuron presumptive rhombomere 2 presumptive rhombomere 4 lateral region presumptive rhombomere 4 motor neuron presumptive rhombomere 4 presumptive telencephalon primary interneuron primary motor neuron primary neuron primary neuron hindbrain proliferative region proneural cluster retina retinal inner nuclear layer rhombomere Rohon-Beard neuron spinal cord neuroblast spinal cord neuron spinal cord spinal cord neural tube spinal neuromere statoacoustic (VIII) ganglion tegmentum telencephalon dorsal region telencephalon thalamus posterior region thalamus third ventricle medial region trigeminal placode trunk neuron unspecified vagal ganglion vagal ganglion 1 vagal ganglion 2 vagal ganglion 3 vagal ganglion 4 vagal placode 1 vagal placode 2 vagal placode 3 vagal placode 4 ventral anterior lateral line ganglion whole organism
Curated Microarray Expression:	GEO (1)

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
hi1059Tg	Transgenic Insertion	Unknown	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)

Targeting reagents:

PHENOTYPE

Data:

25 figures from 16 publications

Observed in:

DISEASE ASSOCIATED WITH neurog1 HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH neurog1 VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	forebrain neuron development (more)
Cellular Component	nucleus (more)
Molecular Function	protein binding (more)

GO Terms (all 29)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR011598 (1) InterPro:IPR032653 (1) InterPro:IPR036638 (1)	PROSITE:PS50888 (1)	Pfam:PF00010 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	neurog1-001 (1)	1393	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION

INTERACTIONS AND PATHWAYS

SignaFish

ANTIBODIES

Ab1-neurog1 (1)

PLASMIDSNo data available

CONSTRUCTS WITH SEQUENCES FROM neurog1

MARKER RELATIONSHIPS

neurog1Contained in:	[BAC] DKEY-171N3 (1) (order this)
neurog1Encodes:	[EST] cb260 (1) (order this) [cDNA] MGC:65737 (1) (order this), MGC:76812 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_131041 (1)	1399bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX571940 (1)	179550bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:O42606 (1)	208aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast
Sequence Clusters	UniGene:75780 (1)

Sequence Information (all 23)

OTHER neurog1 GENE PAGES

Alliance (1)

Gene:30239 (1)

VEGA:OTTDARG00000020942 (1)

Ensembl(GRCz11):ENSDARG00000056130 (1)

ORTHOLOGY for neurog1 (Chr: 14)

CITATIONS (325)

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