Gene

bves

ID
ZDB-GENE-040624-11
Name
blood vessel epicardial substance
Symbol
bves Nomenclature History
Previous Names
  • pop1 (1)
  • popdc1 (1)
  • zgc:86887
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have cAMP binding activity and structural molecule activity. Involved in several processes, including animal organ development; bicellular tight junction assembly; and skeletal myofibril assembly. Localizes to sarcolemma. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2X. Is expressed in several structures, including EVL; cardiovascular system; eye; integument; and optic vesicle. Orthologous to human BVES (blood vessel epicardial substance).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
14 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bves Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive limb-girdle muscular dystrophy type 2X Alliance Muscular dystrophy, limb-girdle, autosomal recessive 25 616812
Associated With bves Via Experimental Models
Human Disease Fish Conditions Citations
tetralogy of Fallot AB + MO1-bves standard conditions Shi et al., 2020
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR006916 Popeye protein
Homologous_superfamily IPR014710 RmlC-like jelly roll fold
Homologous_superfamily IPR018490 Cyclic nucleotide-binding domain superfamily
Domain Details Per Protein
Protein Length Cyclic nucleotide-binding domain superfamily Popeye protein RmlC-like jelly roll fold
UniProtKB:G9HVJ5 352
UniProtKB:Q5PQZ7 352
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-bves polyclonal Rabbit
  • IHC
2
Ab2-bves polyclonal Rabbit
  • IHC
Sigma-Aldrich
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations