Gene

bves

ID
ZDB-GENE-040624-11
Name
blood vessel epicardial substance
Symbol
bves Nomenclature History
Previous Names
  • pop1 (1)
  • popdc1 (1)
  • zgc:86887
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have cAMP binding activity and structural molecule activity. Involved in several processes, including animal organ development; bicellular tight junction assembly; and skeletal myofibril assembly. Localizes to sarcolemma. Is expressed in several structures, including EVL; cardiovascular system; eye; integument; and optic vesicle. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2X. Orthologous to human BVES (blood vessel epicardial substance).
Genome Resources
Note
None
Expression
All Expression Data
13 figures from 4 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bves Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive limb-girdle muscular dystrophy type 2X Alliance Muscular dystrophy, limb-girdle, autosomal recessive 25 616812
Associated With bves Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR006916 Popeye protein
Homologous_superfamily IPR014710 RmlC-like jelly roll fold
Homologous_superfamily IPR018490 Cyclic nucleotide-binding-like
Domain Details Per Protein
Protein Length Cyclic nucleotide-binding-like Popeye protein RmlC-like jelly roll fold
UniProtKB:G9HVJ5 352
UniProtKB:Q5PQZ7 352
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-bves polyclonal Rabbit
  • IHC
2
Ab2-bves polyclonal Rabbit
  • IHC
Sigma-Aldrich
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations