| ZFIN ID: ZDB-GENE-020503-1 |
| Gene Name: | insulin-like growth factor 1a receptor |
|---|---|
| Gene Symbol: | igf1ra |
| Previous Names: | IGF-IRa (1), wu:fi20b10 |
| Nomenclature History | |
| All Expression Data: | 9 figures from 6 publications |
| Wild-type Stages, Structures: | Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult) |
|---|---|
brain,
eye,
gill,
gonad primordium
|
|
| Curated Microarray Expression: | GEO (1) |
| Alleles: | la020321Tg, la020322Tg |
| Knockdown reagents: | MO1-igf1ra (1), MO2-igf1ra (1) |
| Data: | 4 figures from Schlueter et al., 2006 |
| Observed in: |
anterior crista primordium,
CaP motoneuron axon,
cardiac ventricle,
death
|
| Phenotype of Human Orthologue | OMIM Phenotype ID |
|---|---|
| Insulin-like growth factor I, resistance to | 270450 |
| Ontology | GO Term |
|---|---|
| Biological Process | insulin-like growth factor receptor signaling pathway (more) |
| Cellular Component | integral to membrane (more) |
| Molecular Function | insulin-like growth factor binding (more) |
|
|
|
|
|
| Type | Name | Length (bp) | Analysis | |
|---|---|---|---|---|
| mRNA | igf1ra-001 (1) | 5005 |
Select Tool
|
|
| ncRNA | igf1ra-002 (1) | 578 |
Select Tool
|
| Tg(hsp70l:dnigf1ra-EGFP) |
| igf1ra Contained in: | [BAC] CH211-200O3 (1) (order this), DKEY-25F3 (1) (order this) |
| igf1ra Encodes: |
[EST]
fi20b10 (1)
[cDNA] MGC:194803 (1) (order this) |
| Type | Accession # | Length (bp/aa) | Analysis |
|---|---|---|---|
| RNA | RefSeq:NM_152968 (1) | 4257 bp |
Select Tool
|
| Genomic | GenBank:BX470160 (1) | 207501 bp | Blast at MegaBLAST |
| Polypeptide | UniProtKB:Q1LWJ4 (1) | 1405 aa |
Select Tool
|
| Sequence Clusters | UniGene:104808 (1) |
|
|
|
|
| Chr: 18 Details |
| Evidence | ||||||
|---|---|---|---|---|---|---|
| Species | Symbol | Chromosome (Position) | Accession # | AA | CL | |
| Zebrafish | igf1ra | 18 |
|
|
||
| Human | IGF1R | 15 (15q26.3) |
|
|
|
|
| Mouse | Igf1r | 7 ( 37.27) |
|
|
|
|
Request: 