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ZIRC
ZFIN ID: ZDB-GENE-000322-1
Gene Name: actin alpha cardiac muscle 1b
Gene Symbol: actc1b
Sequence Ontology ID : SO:0000704

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Previous Names: acta1, fa27h01, fb83f06, wu:fa27h01 (1), wu:fb83f06 (1)

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have ATP binding activity. Predicted to localize to the cytoplasm and cytoskeleton. Used to study nemaline myopathy. Human ortholog(s) of this gene implicated in atrial heart septal  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027891Tg Transgenic Insertion Unknown Unknown DNA
sa12367 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45589 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH actc1b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    atrial heart septal defect 5 Atrial septal defect 5 612794
    dilated cardiomyopathy 1R Cardiomyopathy, dilated, 1R 613424
    Left ventricular noncompaction 4 613424
    hypertrophic cardiomyopathy 11 Cardiomyopathy, hypertrophic, 11 612098
    DISEASE ASSOCIATED WITH actc1b VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    nemaline myopathy WT + MO1-actc1b standard conditions Sztal et al., 2015
    WT + MO2-actc1b standard conditions Sztal et al., 2015
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 5)
    TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    MARKER RELATIONSHIPS
    actc1bEncodes: [EST] eu184 (1), fa27h01 (1), fb83f06 (1), fc17f05 (1) (order this)
    [cDNA] MGC:55618 (1) (order this), MGC:77653 (1) (order this)
    actc1bHas Artifact: [cDNA] MGC:172132 (1) (order this), MGC:174190 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131591 (1) 1284bp
    Genomic GenBank:CABZ01089194 (1) 30349bp
    Select Tool
    Polypeptide UniProtKB:Q7ZU23 (1) 377aa
    Sequence Clusters UniGene:139231 (1)
    Sequence Information (all 24)
    OTHER actc1b GENE PAGES
  • Alliance (1)
  • Gene:58114 (1)
  • Ensembl(GRCz11):ENSDARG00000099197 (1)
  • ORTHOLOGY for actc1b (Chr: 17)
    CITATIONS (90)