ZFIN ID: ZDB-GENE-000322-1
Gene Name: actin, alpha, cardiac muscle 1b
Gene Symbol: actc1b
Sequence Ontology ID : SO:0000704

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Previous Names: acta1, fa27h01, fb83f06, wu:fa27h01 (1), wu:fb83f06 (1)

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 31 figures from 15 publications
Directly Submitted Expression Data: 6 figures (11 images) from Thisse et al., 2004 [MGC:55618]
  10 figures (31 images) from Rauch et al., 2003 [fc17f05]
  1 figure (1 image) from Thisse et al., 2005 [eu184]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027891Tg Transgenic Insertion Unknown Unknown DNA
sa12367 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45589 Point Mutation Unknown Premature Stop ENU
    Targeting reagents:
    PHENOTYPE
    Data: 6 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH actc1b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    atrial heart septal defect 5 Atrial septal defect 5 612794
    dilated cardiomyopathy 1R Cardiomyopathy, dilated, 1R 613424
    Left ventricular noncompaction 4 613424
    hypertrophic cardiomyopathy 11 Cardiomyopathy, hypertrophic, 11 612098
    DISEASE ASSOCIATED WITH actc1b VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    nemaline myopathy WT + MO1-actc1b standard conditions Sztal et al., 2015
    WT + MO2-actc1b standard conditions Sztal et al., 2015
    GENE ONTOLOGY
    Ontology GO Term
    Molecular Function ATP binding (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004000 (1)
  • InterPro:IPR004001 (1)
  • InterPro:IPR020902 (1)
  • PROSITE:PS00406 (1)
  • PROSITE:PS00432 (1)
  • PROSITE:PS01132 (1)
  • Pfam:PF00022 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM actc1b
    MARKER RELATIONSHIPS
    actc1bEncodes: [EST] eu184 (1), fa27h01 (1), fb83f06 (1), fc17f05 (1) (order this)
    [cDNA] MGC:55618 (1) (order this), MGC:77653 (1) (order this)
    actc1bHas Artifact: [cDNA] MGC:172132 (1) (order this), MGC:174190 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131591 (1) 1284bp
    Genomic GenBank:CABZ01089194 (1) 30349bp
    Select Tool
    Polypeptide UniProtKB:Q7ZU23 (1) 377aa
    Sequence Clusters UniGene:139231 (1)
    Sequence Information (all 24)
    OTHER actc1b GENE PAGES
  • Alliance (1)
  • Gene:58114 (1)
  • Ensembl(GRCz11):ENSDARG00000099197 (1)
  • ORTHOLOGY for actc1b (Chr: 17)
    CITATIONS (85)