ZFIN ID: ZDB-GENE-980526-68
Gene Name: signal transducer and activator of transcription 3 (acute-phase response factor)
Gene Symbol: stat3
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function DNA binding IEA InterPro:IPR013801 ZFIN Electronic Annotation
DNA binding IEA UniProtKB-KW:KW-0238 ZFIN Electronic Annotation
DNA-binding transcription factor activity IEA InterPro:IPR001217 ZFIN Electronic Annotation
DNA-binding transcription factor activity IEA InterPro:IPR008967 ZFIN Electronic Annotation
Cellular Component cytoplasm IEA UniProtKB-KW:KW-0963 ZFIN Electronic Annotation
cytoplasm IEA UniProtKB-SubCell:SL-0086 UniProt-GOA
nucleus IEA InterPro:IPR001217 ZFIN Electronic Annotation
nucleus IEA UniProtKB-KW:KW-0539 ZFIN Electronic Annotation
nucleus IEA UniProtKB-SubCell:SL-0191 UniProt-GOA
Biological Process axis elongation IMP stat3stl27/stl27 Liu et al., 2017
axis elongation IMP stat3stl27 Liu et al., 2017
cardiac muscle tissue regeneration IMP pd13Tg/+; pd59Tg/+ Fang et al., 2013
cell migration involved in gastrulation IMP Yamashita et al., 2004
epithelial to mesenchymal transition IMP Yamashita et al., 2004
establishment of cell polarity IMP Miyagi et al., 2004
establishment of planar polarity IMP Miyagi et al., 2004
inner ear receptor cell development IMP MO1-stat3 Liang et al., 2012
motor neuron axon guidance IMP MO2-stat3 Conway, 2006
positive regulation of glial cell proliferation IMP MO1-stat3 Kassen et al., 2009
positive regulation of glial cell proliferation IMP MO3-stat3 Kassen et al., 2009
posterior lateral line neuromast hair cell development IMP MO1-stat3 Liang et al., 2012
receptor signaling pathway via JAK-STAT IMP pd13Tg/+; pd59Tg/+ Fang et al., 2013
regeneration IGI socs3a Liang et al., 2012
regulation of cell population proliferation IMP stat3stl27/stl27 Liu et al., 2017
regulation of cell population proliferation IMP stat3stl27 Liu et al., 2017
regulation of cell shape IMP stat3stl27/stl27 Liu et al., 2017
regulation of cell shape IMP stat3stl27 Liu et al., 2017
regulation of cell size IMP stat3stl27/stl27 Liu et al., 2017
regulation of cell size IMP stat3stl27 Liu et al., 2017
regulation of transcription, DNA-templated IEA InterPro:IPR001217 ZFIN Electronic Annotation
regulation of transcription, DNA-templated IEA InterPro:IPR008967 ZFIN Electronic Annotation
regulation of transcription, DNA-templated IEA InterPro:IPR013799 ZFIN Electronic Annotation
regulation of transcription, DNA-templated IEA InterPro:IPR013800 ZFIN Electronic Annotation
regulation of transcription, DNA-templated IEA InterPro:IPR015988 ZFIN Electronic Annotation
retina morphogenesis in camera-type eye IMP MO3-stat3 Yin et al., 2012
signal transduction IEA InterPro:IPR001217 ZFIN Electronic Annotation
signal transduction IEA InterPro:IPR013799 ZFIN Electronic Annotation
signal transduction IEA InterPro:IPR013800 ZFIN Electronic Annotation
signal transduction IEA InterPro:IPR015988 ZFIN Electronic Annotation
skeletal system development IMP stat3stl28/stl28 Liu et al., 2017
skeletal system development IMP stat3stl27/stl27 Liu et al., 2017
skeletal system development IMP stat3sa15744/sa15744 Liu et al., 2017