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ZIRC
ZFIN ID: ZDB-GENE-980526-68
Gene Name: signal transducer and activator of transcription 3 (acute-phase response factor)
Gene Symbol: stat3
Sequence Ontology ID : SO:0000704

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Previous Names: z-Stat3 (1), wu:fc15d02 (1), wu:fl59g06 (1)

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(Including Attributions)
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in several  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb211 Indel Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb212 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • sa938 Point Mutation Unknown Splice Site ENU
    sa10162 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12185 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15744 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16856 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • stl27 Small Deletion Exon 5 Frameshift, Premature Stop TALEN
    stl28 Indel Exon 5 Frameshift, Premature Stop TALEN
    Targeting reagents:
    DISEASE ASSOCIATED WITH stat3 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Job's syndrome Hyper-IgE recurrent infection syndrome 147060
    Autoimmune disease, multisystem, infantile-onset, 1 615952
    DISEASE ASSOCIATED WITH stat3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regeneration (more)
    Cellular Component cytoplasm (more)
    Molecular Function DNA binding (more)
    GO Terms (all 33)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA stat3-003 (1) 2717
    mRNA stat3-201 (1) 2742
    stat3-202 (1) 3055
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES
    PLASMIDSNo data available
    MARKER RELATIONSHIPS
    stat3Contained in: [BAC] CH211-209D14 (1) (order this)
    stat3Encodes: [EST] eu734 (1), fc15d02 (1), fl59g06 (1)
    [cDNA] MGC:55197 (1) (order this), MGC:85598 (1) (order this), MGC:193054 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131479 (1) 3071bp
    Genomic GenBank:CR847978 (1) 194409bp
    Select Tool
    Polypeptide UniProtKB:C0SPC7 (1) 806aa
    Sequence Clusters UniGene:132860 (1)
    Sequence Information (all 48)
    ORTHOLOGY for stat3 (Chr: 3)
    CITATIONS (105)