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General Information
ZIRC
ZFIN ID: ZDB-GENE-021030-4
Gene Name: carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Gene Symbol: cad
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function amino acid binding IEA InterPro:IPR006130 ZFIN Electronic Annotation
amino acid binding IEA InterPro:IPR006131 ZFIN Electronic Annotation
amino acid binding IEA InterPro:IPR036901 ZFIN Electronic Annotation
aspartate carbamoyltransferase activity IBA FB:FBgn0003189, PomBase:SPAC22G7.06c, PANTHER:PTN000150227, SGD:S000003666, RGD:1588606 Gaudet et al., 2010
aspartate carbamoyltransferase activity IEA InterPro:IPR002082 ZFIN Electronic Annotation
ATP binding IEA UniRule:UR000414645 UniProt curators
ATP binding IEA InterPro:IPR005479 ZFIN Electronic Annotation
ATP binding IEA InterPro:IPR011761 ZFIN Electronic Annotation
ATP binding IEA InterPro:IPR013815 ZFIN Electronic Annotation
ATP binding IEA UniProtKB-KW:KW-0067 ZFIN Electronic Annotation
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity IEA InterPro:IPR006274 ZFIN Electronic Annotation
CONTRIBUTES TO carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity IBA PANTHER:PTN000150223, EcoGene:EG10135, SGD:S000003870 Gaudet et al., 2010
carboxyl- or carbamoyltransferase activity IEA InterPro:IPR006130 ZFIN Electronic Annotation
carboxyl- or carbamoyltransferase activity IEA InterPro:IPR006131 ZFIN Electronic Annotation
carboxyl- or carbamoyltransferase activity IEA InterPro:IPR006132 ZFIN Electronic Annotation
carboxyl- or carbamoyltransferase activity IEA InterPro:IPR036901 ZFIN Electronic Annotation
dihydroorotase activity IBA FB:FBgn0003189, PANTHER:PTN000150227, UniProtKB:P27708, RGD:1588606 Gaudet et al., 2010
hydrolase activity IEA InterPro:IPR006680 ZFIN Electronic Annotation
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds IEA InterPro:IPR011059 ZFIN Electronic Annotation
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides IEA InterPro:IPR002195 ZFIN Electronic Annotation
metal ion binding IEA InterPro:IPR011761 ZFIN Electronic Annotation
nucleotide binding IEA UniProtKB-KW:KW-0547 ZFIN Electronic Annotation
Cellular Component cytoplasm IBA EcoGene:EG10805, MGI:MGI:891996, RGD:2395, SGD:S000003666, PANTHER:PTN000150222, SGD:S000003870, UniProtKB:P31327, RGD:1588606, UniProtKB:Q9LVW7, TAIR:locus:2019302, EcoGene:EG10134, TAIR:locus:2092369, EcoGene:EG10135, UniProtKB:P27708, SGD:S000005829 Gaudet et al., 2010
cytoplasm IBA EcoGene:EG10805, MGI:MGI:891996, RGD:2395, SGD:S000003666, PANTHER:PTN000150222, SGD:S000003870, RGD:1588606, UniProtKB:P31327, TAIR:locus:2019302, UniProtKB:Q9LVW7, TAIR:locus:2092369, EcoGene:EG10134, EcoGene:EG10135, UniProtKB:P27708, SGD:S000005829 Gaudet et al., 2010
cytosol IBA PANTHER:PTN000150227, UniProtKB:P27708, RGD:1588606 Gaudet et al., 2010
Biological Process 'de novo' pyrimidine nucleobase biosynthetic process IBA FB:FBgn0003189, PomBase:SPAC22G7.06c, PANTHER:PTN000150227, SGD:S000003666, UniProtKB:P27708, RGD:1588606 Gaudet et al., 2010
'de novo' pyrimidine nucleobase biosynthetic process IEA InterPro:IPR002082 ZFIN Electronic Annotation
'de novo' pyrimidine nucleobase biosynthetic process IEA InterPro:IPR006274 ZFIN Electronic Annotation
'de novo' pyrimidine nucleobase biosynthetic process IMP cada52/a52 Willer et al., 2005
cellular amino acid metabolic process IEA InterPro:IPR006130 ZFIN Electronic Annotation
cellular amino acid metabolic process IEA InterPro:IPR006131 ZFIN Electronic Annotation
cellular amino acid metabolic process IEA InterPro:IPR006132 ZFIN Electronic Annotation
cellular amino acid metabolic process IEA InterPro:IPR036901 ZFIN Electronic Annotation
citrulline biosynthetic process IBA PANTHER:PTN000150227, RGD:1588606 Gaudet et al., 2010
facial nerve morphogenesis IMP cadsl23/sl23 Cox et al., 2014
glossopharyngeal nerve morphogenesis IMP cadsl23/sl23 Cox et al., 2014
glutamine metabolic process IBA FB:FBgn0003189, PomBase:SPAC22G7.06c, PANTHER:PTN000150223, SGD:S000003666, dictyBase:DDB_G0276335, RGD:1588606 Gaudet et al., 2010
glutamine metabolic process IEA InterPro:IPR006274 ZFIN Electronic Annotation
glutamine metabolic process IEA UniProtKB-KW:KW-0315 ZFIN Electronic Annotation
lymphangiogenesis IMP cadhu10125/hu10125 Coxam et al., 2015
neuron projection morphogenesis IMP cadsl23/sl23 Cox et al., 2014
nitrogen compound metabolic process IBA PomBase:SPAC22G7.06c, RGD:2395, SGD:S000003666, PANTHER:PTN000150222, SGD:S000003870, PomBase:SPBC215.08c, dictyBase:DDB_G0276335, RGD:1588606, UniProtKB:P31327, FB:FBgn0003189, PomBase:SPBC56F2.09c, UniProtKB:P38100, TAIR:locus:2092369, EcoGene:EG10134, EcoGene:EG10135, WB:WBGene00004259, UniProtKB:P27708, SGD:S000005829 Gaudet et al., 2010
nitrogen compound metabolic process IBA PomBase:SPAC22G7.06c, RGD:2395, SGD:S000003666, PANTHER:PTN000150222, SGD:S000003870, PomBase:SPBC215.08c, dictyBase:DDB_G0276335, RGD:1588606, UniProtKB:P31327, FB:FBgn0003189, PomBase:SPBC56F2.09c, EcoGene:EG10134, UniProtKB:P38100, TAIR:locus:2092369, EcoGene:EG10135, UniProtKB:P27708, WB:WBGene00004259, SGD:S000005829 Gaudet et al., 2010
nitrogen compound metabolic process IEA InterPro:IPR005483 ZFIN Electronic Annotation
nitrogen compound metabolic process IEA InterPro:IPR006275 ZFIN Electronic Annotation
regulation of Notch signaling pathway IMP cadhu10125/hu10125 Coxam et al., 2015
regulation of vascular endothelial growth factor receptor signaling pathway IGI cadhu10125/hu10125 , MO3-flt4 Coxam et al., 2015
regulation of vascular endothelial growth factor signaling pathway IGI cadhu10125/hu10125 , MO1-vegfc Coxam et al., 2015
retina development in camera-type eye IMP cada52/a52 Link et al., 2001
trigeminal nerve morphogenesis IMP cadsl23/sl23 Cox et al., 2014
UTP biosynthetic process IBA PANTHER:PTN000150227, RGD:1588606 Gaudet et al., 2010
vagus nerve morphogenesis IMP cadsl23/sl23 Cox et al., 2014