ZFIN

ZFIN ID: ZDB-GENE-040426-2266

ZFIN ID: ZDB-GENE-040426-2266

CITATIONS (56 total)

Gene Name:	phosphoenolpyruvate carboxykinase 2 (mitochondrial)
Gene Symbol:	pck2

Hu, W., Liu, L., Forn-Cuní, G., Ding, Y., Alia, A., Spaink, H.P. (2023) Transcriptomic and Metabolomic Studies Reveal That Toll-like Receptor 2 Has a Role in Glucose-Related Metabolism in Unchallenged Zebrafish Larvae (Danio rerio). Biology. 12(2):

Li, L., Chen, M., Liu, W., Tai, P., Liu, X., Liu, J.X. (2022) Zebrafish cox17 modulates primitive erythropoiesis via regulation of mitochondrial metabolism to facilitate hypoxia tolerance. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 36:e22596

Pozo-Morales, M., Garteizgogeascoa, I., Perazzolo, C., So, J., Shin, D., Singh, S.P. (2022) In vivo imaging of calcium dynamics in zebrafish hepatocytes. Hepatology (Baltimore, Md.). 77(3):789-801

Tabler, C.T., Lodd, E., Bennewitz, K., Middel, C.S., Erben, V., Ott, H., Poth, T., Fleming, T., Morgenstern, J., Hausser, I., Sticht, C., Poschet, G., Szendroedi, J., Nawroth, P.P., Kroll, J. (2022) Loss of glyoxalase 2 alters the glucose metabolism in zebrafish. Redox Biology. 59:102576102576

Banerji, R., Huynh, C., Figueroa, F., Dinday, M.T., Baraban, S.C., Patel, M. (2021) Enhancing glucose metabolism via gluconeogenesis is therapeutic in a zebrafish model of Dravet syndrome. Brain communications. 3:fcab004

Blanco, A.M., Bertucci, J.I., Hatef, A., Unniappan, S. (2020) Feeding and food availability modulate brain-derived neurotrophic factor, an orexigen with metabolic roles in zebrafish. Scientific Reports. 10:10727

Blanco, A.M., Bertucci, J.I., Unniappan, S. (2020) FGF21 Mimics a Fasting-Induced Metabolic State and Increases Appetite in Zebrafish. Scientific Reports. 10:6993

Rajeswari, J.J., Blanco, A.M., Unniappan, S. (2020) Phoenixin-20 (PNX-20) Suppresses Food Intake, Modulates Glucoregulatory Enzymes, and Enhances Glycolysis in Zebrafish. American journal of physiology. Regulatory, integrative and comparative physiology. 318(5):R917-R928

Wang, L., Lin, W., Zha, Q., Guo, H., Zhang, D., Yang, L., Li, L., Li, D., Tang, R. (2020) Persistent Exposure to Environmental Levels of Microcystin-LR Disturbs Cortisol Production via Hypothalamic-Pituitary-Interrenal (HPI) Axis and Subsequently Liver Glucose Metabolism in Adult Male Zebrafish (Danio rerio). toxins. 12(5):

Wang, X., Sun, S., Cao, X., Gao, J. (2020) Quantitative Phosphoproteomic Analysis Reveals the Regulatory Networks of Elovl6 on Lipid and Glucose Metabolism in Zebrafish. International Journal of Molecular Sciences. 21(8):

Yang, Y., Dong, F., Liu, X., Xu, J., Wu, X., Zheng, Y. (2020) Thifluzamide induces the toxic effects on zebrafish (Danio rerio) via inhibition of succinate dehydrogenase (SDH). Environmental pollution (Barking, Essex : 1987). 265:115031

Morbiato, E., Frigato, E., Dinarello, A., Maradonna, F., Facchinello, N., Argenton, F., Carnevali, O., Dalla Valle, L., Bertolucci, C. (2019) Feeding Entrainment of the Zebrafish Circadian Clock Is Regulated by the Glucocorticoid Receptor. Cells. 8(11):

Chen, L., Wang, Y., Giesy, J.P., Chen, F., Shi, T., Chen, J., Xie, P. (2018) Microcystin-LR affects the hypothalamic-pituitary-inter-renal (HPI) axis in early life stages (embryos and larvae) of zebrafish. Environmental pollution (Barking, Essex : 1987). 241:540-548

Mishra, S., Wu, S.Y., Fuller, A.W., Wang, Z., Rose, K.L., Schey, K.L., Mchaourab, H.S. (2018) Loss of αB-crystallin function in zebrafish reveals critical roles in the development of the lens and stress resistance of the heart. The Journal of biological chemistry. 293(2):740-753

Zhao, F., Jiang, G., Wei, P., Wang, H., Ru, S. (2018) Bisphenol S exposure impairs glucose homeostasis in male zebrafish (Danio rerio). Ecotoxicology and environmental safety. 147:794-802

Zhao, F., Wang, H., Wei, P., Jiang, G., Wang, W., Zhang, X., Ru, S. (2018) Impairment of bisphenol F on the glucose metabolism of zebrafish larvae. Ecotoxicology and environmental safety. 165:386-392

Cortés, R., Teles, M., Oliveira, M., Fierro-Castro, C., Tort, L., Cerdá-Reverter, J.M. (2017) Effects of acute handling stress on short-term central expression of orexigenic/anorexigenic genes in zebrafish. Fish physiology and biochemistry. 44(1):257-272

Rauwerda, H., Pagano, J.F., de Leeuw, W.C., Ensink, W., Nehrdich, U., de Jong, M., Jonker, M., Spaink, H.P., Breit, T.M. (2017) Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. BMC Genomics. 18:287

Zhang, C.Y., Yin, H.M., Wang, H., Su, D., Xia, Y., Yan, L.F., Fang, B., Liu, W., Wang, Y.M., Gu, A.H., Zhou, Y. (2017) Transforming growth factor-β1 regulates the nascent hematopoietic stem cell niche by promoting gluconeogenesis. Leukemia. 32(2):479-491

Chen, Q., Jia, A., Snyder, S.A., Gong, Z., Lam, S.H. (2016) Glucocorticoid activity detected by in vivo zebrafish assay and in vitro glucocorticoid receptor bioassay at environmental relevant concentrations. Chemosphere. 144:1162-1169

Kumar, M.G., Rowley, S., Fulton, R., Dinday, M.T., Baraban, S.C., Patel, M. (2016) Altered Glycolysis and Mitochondrial Respiration in a Zebrafish Model of Dravet Syndrome. eNeuro. 3(2):e0008-16

Michel, M., Page-McCaw, P.S., Chen, W., Cone, R.D. (2016) Leptin signaling regulates glucose homeostasis, but not adipostasis, in the zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 113(11):3084-9

Zhao, Y., Zhang, K., Fent, K. (2016) Corticosteroid Fludrocortisone Acetate Targets Multiple End Points in Zebrafish (Danio rerio) at Low Concentrations. Environmental science & technology. 50(18):10245-54

Chatzopoulou, A., Roy, U., Meijer, A.H., Alia, A., Spaink, H.P., Schaaf, M.J. (2015) Transcriptional and Metabolic Effects of Glucocorticoid Receptor α and β Signaling in Zebrafish. Endocrinology. 156(5):1757-69

Furukawa, F., Tseng, Y.C., Liu, S.T., Chou, Y.L., Lin, C.C., Sung, P.H., Uchida, K., Lin, L.Y., Hwang, P.P. (2015) Induction of Phosphoenolpyruvate Carboxykinase (PEPCK) during Acute Acidosis and Its Role in Acid Secretion by V-ATPase-Expressing Ionocytes. International journal of biological sciences. 11(6):712-725

Li, M., Dean, E.D., Zhao, L., Nicholson, W.E., Powers, A.C., Chen, W. (2015) Glucagon receptor inactivation leads to α-cell hyperplasia in zebrafish. The Journal of endocrinology. 227:93-103

Zhang, X., Zhong, Y., Tian, H., Wang, W., Ru, S. (2015) Impairment of the cortisol stress response mediated by the hypothalamus-pituitary-interrenal (HPI) axis in zebrafish (Danio rerio) exposed to monocrotophos pesticide. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 176-177:10-6

Howarth, D.L., Lindtner, C., Vacaru, A.M., Sachidanandam, R., Tsedensodnom, O., Vasilkova, T., Buettner, C., Sadler, K.C. (2014) Activating transcription factor 6 is necessary and sufficient for alcoholic Fatty liver disease in zebrafish. PLoS Genetics. 10:e1004335

Fu, J., Han, J., Zhou, B., Gong, Z., Santos, E.M., Huo, X., Zheng, W., Liu, H., Yu, H., and Liu, C. (2013) Toxicogenomic Responses of Zebrafish Embryos/Larvae to Tris(1,3-dichloro-2-propyl) Phosphate (TDCPP) Reveal Possible Molecular Mechanisms of Developmental Toxicity. Environmental science & technology. 47(18):10574-82

Seiliez, I., Médale, F., Aguirre, P., Larquier, M., Lanneretonne, L., Alami-Durante, H., Panserat, S., and Skiba-Cassy, S. (2013) Postprandial regulation of growth- and metabolism-related factors in zebrafish. Zebrafish. 10(2):237-248

Jurczyk, A., Roy, N., Bajwa, R., Gut, P., Lipson, K., Yang, C., Covassin, L., Racki, W.J., Rossini, A.A., Phillips, N., Stainier, D.Y., Greiner, D.L., Brehm, M.A., Bortell, R., and diIorio, P. (2011) Dynamic glucoregulation and mammalian-like responses to metabolic and developmental disruption in zebrafish. General and comparative endocrinology. 170(2):334-345

Sato, Y., Hashiguchi, Y., and Nishida, M. (2009) Temporal pattern of loss/persistence of duplicate genes involved in signal transduction and metabolic pathways after teleost-specific genome duplication. BMC Evolutionary Biology. 9:127

Hart, D.O., Raha, T., Lawson, N.D., and Green, M.R. (2007) Initiation of zebrafish haematopoiesis by the TATA-box-binding protein-related factor Trf3. Nature. 450(7172):1082-1085

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Additional Citations (22):

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2012) Gene Ontology annotation based on UniPathway vocabulary mapping. Manually curated data.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

Thisse, B., Thisse, C. (2004) Fast Release Clones: A High Throughput Expression Analysis. ZFIN Direct Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2003) Curation of unpublished nucleotide sequence accession numbers. Manually curated data.

ZFIN Staff (2003) Gene Ontology Annotation Through Association of Enzyme Commission numbers with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.

Kudoh, T., Tsang, M., Hukriede, N.A., Chen, X., Dedekian, M., Clarke, C.J., Kiang, A., Schultz, S., Epstein, J.A., Toyama, R., and Dawid, I.B. (2001) A gene expression screen in zebrafish embryogenesis. ZFIN Direct Data Submission.