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ZIRC
ZFIN ID: ZDB-GENE-040426-2266
Gene Name: phosphoenolpyruvate carboxykinase 2 (mitochondrial)
Gene Symbol: pck2    Nomenclature History

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Previous Names: id:ibd5157, zgc:77867

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have manganese ion binding activity and phosphoenolpyruvate carboxykinase (GTP) activity. Predicted to be involved in several processes, including cellular response to hormone stimulus; gluconeogenesis; and monocarboxylic acid metabolic process. Predicted to localize to the cytosol and mitochondrion. Is expressed in extension; intestinal bulb; liver; and yolk syncytial layer. Orthologous to human PCK2 (phosphoenolpyruvate carboxykinase 2, mitochondrial).
Genome Resources: Alliance (1),  Gene:406473 (1),  Ensembl(GRCz11):ENSDARG00000020956 (1)
GENE EXPRESSION
All Expression Data: 19 figures from 9 publications
Directly Submitted Expression Data: 3 figures (4 images) from Kudoh et al., 2001 [ibd5157]
  7 figures (13 images) from Thisse et al., 2004 [IMAGE:7152622]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17973 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44105 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pck2 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    PEPCK deficiency, mitochondrial 261650
    DISEASE ASSOCIATED WITH pck2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process gluconeogenesis (more)
    Cellular Component cytosol (more)
    Molecular Function GTP binding (more)
    GO Terms (all 17)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pck2-201 (1)    Ensembl 3414
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pck2 No data available
    MARKER RELATIONSHIPS
    pck2 Contained in: [BAC] DKEYP-28D2 (1)
    pck2 Encodes: [EST] ibd5157 (1) (order this), IMAGE:7152622 (1) (order this)
    [cDNA] MGC:77867 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213192 (1) 3067 bp
    Genomic GenBank:CR405710 (1) 185586 bp
    Select Tool
    Polypeptide UniProtKB:F1R9Y5 (1) 636 aa
    Sequence Clusters UniGene:132490 (1)
    Sequence Information (all 13)
    ORTHOLOGY for pck2 ( Chr: 24 )
    CITATIONS (41)