ZFIN Image: Olson et al., 2024, Fig. 1.

Image

Figure Caption

Fig. 1.

Identification of the pLLP transcriptional profile by scRNA-seq. (A) Unsupervised clustering and UMAP reduction diagram of cells derived from Tg(-8.0claudinB: lynGFP)^zf106; TgBAC(cxcr4b:F-tractin-mCherry)^p3 embryos. (B,C) Feature plots of hmx2 and hmx3a identify clusters 0, 7 and 9 as pLLP. (D) Unsupervised reclustering of clusters 0, 7 and 9. (E,F) Feature plots of ki67 and pcna identify cluster 2 as proliferating cells. (G,H) Feature plots of lef1 and notum1a identify cluster 1 as leader cells. (I,J) Feature plots of etv4 and ackr3b identify cluster 0 as follower cells.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development