Gene

ackr3b

ID
ZDB-GENE-031116-61
Name
atypical chemokine receptor 3b
Symbol
ackr3b Nomenclature History
Previous Names
  • CXCR7 (1)
  • cxcr7b (1)
  • drRDC1b (1)
  • sb:cb900
  • si:dkey-96h14.2
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Enables chemokine binding activity. Acts upstream of or within several processes, including blood vessel morphogenesis; nervous system development; and posterior lateral line neuromast primordium migration. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including anterior neural keel; hindbrain neural keel; immature eye; nervous system; and neural rod. Orthologous to human ACKR3 (atypical chemokine receptor 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
46 figures from 29 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
21 figures from 10 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ackr3b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Oculomotor-abducens synkinesis 619215
Associated With ackr3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR001416 Atypical chemokine receptor 3
Domain Details Per Protein
Protein Length Atypical chemokine receptor 3 GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like
UniProtKB:A8KBU0 362
UniProtKB:A4IG54 362
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-ackr3b monoclonal Mouse
  • IHC
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations