ZFIN ID: ZDB-GENE-001020-1
Gene Name: H6 family homeobox 3a
Gene Symbol: hmx3a    Nomenclature History

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Previous Names: hmx3, Nkx5-1, nkx5.1, zgc:109845

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have sequence-specific DNA binding activity. Involved in inner ear morphogenesis and posterior lateral line development. Predicted to localize to nucleus. Is expressed in dorsolateral placode; nervous system; neural rod; neural tube; and otic vesicle. Orthologous to human HMX3 (H6 family homeobox 3).
Genome Resources: Alliance (1),  Gene:60310 (1),  Ensembl(GRCz11):ENSDARG00000070955 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa23054 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • su3 Indel Unknown Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-hmx3a
    1
    CRISPR2-hmx3a 1
    MO1-hmx3a N/A 1
    MO2-hmx3a N/A 1
    MO3-hmx3a N/A 1
    DISEASE ASSOCIATED WITH hmx3a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hmx3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process inner ear morphogenesis (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hmx3a-201 (1)    Ensembl 2121
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hmx3a
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    tg(hsp70l:hmx3a) hsp70l hmx3a Danio rerio 1 1
    MARKER RELATIONSHIPS
    hmx3a Contained in: [BAC] CH211-208G24 (1)
    hmx3a Encodes: [EST] eu350 (1)
    [cDNA] MGC:109845 (1), MGC:191416 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131634 (1) 2065 nt
    Genomic GenBank:AL773596 (1) 206778 nt Blast at MegaBLAST
    Polypeptide UniProtKB:B2GP77 (1) 297 aa
    Sequence Information (all 25)
    ORTHOLOGY for hmx3a ( Chr: 17 )
    CITATIONS (56)