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Gene

etv4

ID
ZDB-GENE-990415-71
Name
ETS variant transcription factor 4
Symbol
etv4 Nomenclature History
Previous Names
  • etID309954.12 (1)
  • pea3 (1)
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Enables sequence-specific DNA binding activity. Involved in positive regulation of transcription, DNA-templated. Acts upstream of or within limb morphogenesis and pronephric nephron tubule epithelial cell differentiation. Predicted to be active in nucleus. Is expressed in several structures, including fin; head; mesoderm; nervous system; and neural keel. Orthologous to human ETV4 (ETS variant transcription factor 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
110 figures from 78 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Marra et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With etv4 Human Ortholog
No data available
Associated With etv4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000418 Ets domain
Domain IPR006715 PEA3-type ETS-domain transcription factor, N-terminal
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Ets domain PEA3-type ETS-domain transcription factor, N-terminal Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:Q9PUQ1 494
UniProtKB:F1RD02 494
UniProtKB:Q6NYQ6 494
UniProtKB:F1R9U5 263
UniProtKB:F8W5E8 195
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations