ZFIN ID: ZDB-GENE-990415-14
Gene Name: apolipoprotein A-Ia
Gene Symbol: apoa1a
Previous Names: apoa, apoa1, cb49 (1), etID309895.5 (1), etID32161.5 (1), wu:fb33f01 (1), zgc:103718
Location: Chr: 5   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 11 figures from 6 publications
Directly Submitted Expression Data: 6 figures (2 images) from Thisse et al., 2001 [cb49]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
  intestine, liver, ovary, unspecified (all 5) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa10582
Knockdown reagents: MO1-apoa1a (1)
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Amyloidosis, 3 or more types 105200
ApoA-I and apoC-III deficiency, combined
Corneal clouding, autosomal recessive
Hypoalphalipoproteinemia 604091
GENE ONTOLOGY
Ontology GO Term
Biological Process cholesterol biosynthetic process (more)
Cellular Component extracellular region (more)
Molecular Function cholesterol transporter activity (more)
GO Terms (all 16)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000074 (1)
  • Pfam:PF01442 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA apoa1a-001 (1) 974
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM apoa1a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    apoa1a Contained in: [BAC] CH211-139A5 (1) (order this)
    apoa1a Encodes: [EST] cb49 (1) (order this), fb33f01 (1)
    [cDNA] MGC:103718 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131128 (1) 1004 bp
    Genomic GenBank:BX465852 (1) 160041 bp
    Select Tool
    Polypeptide UniProtKB:O42363 (1) 262 aa
    Sequence Clusters UniGene:75775 (1)
    Sequence Information (all 16)
    OTHER apoa1a GENE PAGES
  • Gene:30355 (1)
  • VEGA:OTTDARG00000011440 (1)
  • Ensembl(Zv9):ENSDARG00000012076 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish apoa1a 5  
    Human APOA1 11 (11q23-q24)
  • OMIM:107680
  • Gene:335
  • Mouse Apoa1 9 ( 25.36 cM)
  • MGI:88049
  • Gene:11806
  • Orthology Details
    CITATIONS (47)