ZFIN Gene: apoa1a

ZFIN ID: ZDB-GENE-990415-14

ZFIN ID: ZDB-GENE-990415-14

Gene Name:	apolipoprotein A-Ia
Gene Symbol:	apoa1a
Previous Names:	apoa, apoa1, cb49 (1), etID309895.5 (1), etID32161.5 (1), wu:fb33f01 (1), zgc:103718
Location:	Chr: 5 Details
Nomenclature History

GENE EXPRESSION
All Expression Data:	11 figures from 6 publications
Directly Submitted Expression Data:	6 figures (2 images) from Thisse et al., 2001 [cb49]
Wild-type Stages, Structures:	Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
	intestine , liver , ovary , unspecified (all 5)
Curated Microarray Expression:	GEO (1)

MUTANTS AND TARGETED KNOCKDOWNS

Alleles:	sa10582
Knockdown reagents:	MO1-apoa1a (1)

PHENOTYPE

Phenotype of Human Orthologue	OMIM Phenotype ID
Amyloidosis, 3 or more types	105200
ApoA-I and apoC-III deficiency, combined
Corneal clouding, autosomal recessive
Hypoalphalipoproteinemia	604091

GENE ONTOLOGY

Ontology	GO Term
Biological Process	cholesterol biosynthetic process (more)
Cellular Component	extracellular region (more)
Molecular Function	cholesterol transporter activity (more)

GO Terms (all 34)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR000074 (1)	Pfam:PF01442 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	apoa1a-001 (1)	974	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega

GENE PRODUCT DESCRIPTION

ANTIBODIES No data available

PLASMIDS No data available

CONSTRUCTS WITH SEQUENCES FROM apoa1a No data available

SEGMENT (CLONE AND PROBE) RELATIONSHIPS

apoa1a Contained in:	[BAC] CH211-139A5 (1) (order this)
apoa1a Encodes:	[EST] cb49 (1) (order this), fb33f01 (1) [cDNA] MGC:103718 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_131128 (1)	1004 bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
Genomic	GenBank:BX465852 (1)	160041 bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:O42363 (1)	262 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast Vega Protein Blast
Sequence Clusters	UniGene:75775 (1)

OTHER apoa1a GENE PAGES

Gene:30355 (1)

VEGA:OTTDARG00000011440 (1)

Ensembl(Zv9):ENSDARG00000012076 (1)

ORTHOLOGY

CITATIONS (48)