ZFIN ID: ZDB-GENE-990415-14
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.
Gene Name: apolipoprotein A-Ia
Gene Symbol: apoa1a
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: apoa1, apoa, cb49 (1), etID309895.5 (1), etID32161.5 (1), wu:fb33f01 (1), zgc:103718

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 18 figures from 11 publications
Directly Submitted Expression Data: 6 figures (2 images) from Thisse et al., 2001 [cb49]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10582 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH apoa1a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    familial visceral amyloidosis Amyloidosis, 3 or more types 105200
    Corneal clouding, autosomal recessive
    ApoA-I and apoC-III deficiency, combined
    Hypoalphalipoproteinemia 604091
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cholesterol biosynthetic process (more)
    Cellular Component extracellular region (more)
    Molecular Function cholesterol transporter activity (more)
    GO Terms (all 34)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000074 (1)
    		•
  • Pfam:PF01442 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA apoa1a-001 (1) 974
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM apoa1a No data available
    MARKER RELATIONSHIPS
    apoa1aContained in: [BAC] CH211-139A5 (1) (order this)
    apoa1aEncodes: [EST] cb49 (1) (order this), fb33f01 (1)
    [cDNA] MGC:103718 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131128 (1) 1004bp
    Select Tool
    Genomic GenBank:BX465852 (1) 160041bp
    Select Tool
    Polypeptide UniProtKB:O42363 (1) 262aa
    Select Tool
    Sequence Clusters UniGene:75775 (1)
    Sequence Information (all 17)
    OTHER apoa1a GENE PAGES
  • Alliance (1)
  • Gene:30355 (1)
  • VEGA:OTTDARG00000011440 (1)
    • ORTHOLOGY for apoa1a (Chr: 5)
    CITATIONS (67)