Schvarzstein, M., Kirn, A., Haffter, P., and Cordes, S.P. (1999) Expression of zkrml2, a homologue of the Krml1/val segmentation gene, during embryonic patterning of the zebrafish. Mechanisms of Development. 80(2):223-226.
We have identified Zkrml2, a novel homologue of the segmentation gene Krml/val in zebrafish (Danio rerio). Zkrml2 shows 72% and 92% identity in its basic leucine zipper domain with mouse Krml1 and zebrafish val, respectively. Zkrml2 is expressed coincident with MyoD throughout the somites starting at the three somite stage, becomes restricted to the dermomyotome, and subsequently disappears. Transient expression is also detected in the reticulospinal and oculomotor neurons. Zkrml2 maps to the Oregon linkage group 11 (Boston Linkage group 14) with no mapped zebrafish mutations nearby.