ZFIN ID: ZDB-GENE-091204-403
Gene Name: complexin 3b
Gene Symbol: cplx3b    Nomenclature History

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Previous Name: si:ch1073-122j16.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have SNARE binding activity. Predicted to be involved in regulation of neurotransmitter secretion and synaptic vesicle exocytosis. Predicted to localize to SNARE complex and terminal bouton. Is expressed in female organism. Orthologous to human CPLX3 (complexin 3).
Genome Resources: Alliance (1),  Gene:794623 (1),  Ensembl(GRCz11):ENSDARG00000089486 (2)
GENE EXPRESSION
All Expression Data: Table S1 from Newman et al., 2019
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la020527Tg Transgenic Insertion Unknown Unknown DNA
PHENOTYPE No data available
DISEASE ASSOCIATED WITH cplx3b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH cplx3b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process neurotransmitter transport (more)
Cellular Component SNARE complex (more)
Molecular Function syntaxin binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA cplx3b-201 (1)    Ensembl 601
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-cplx3/4 polyclonal Rabbit IHC, WB Synaptic Systems GmbH
2
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM cplx3b No data available
MARKER RELATIONSHIPS
cplx3b Contained in: [Fosmid] CH1073-122J16 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001171590 (1) 877 nt
Genomic GenBank:CU607071 (1) 31691 nt
Select Tool
Polypeptide UniProtKB:D2K290 (1) 156 aa
Sequence Information (all 9)
ORTHOLOGY for cplx3b ( Chr: 18 )
CITATIONS (19)