ZFIN ID: ZDB-GENE-060526-116
Gene Name: complexin 4a
Gene Symbol: cplx4a    Nomenclature History

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Previous Names: si:ch211-233a1.5, zgc:153429

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have SNARE binding activity. Involved in regulation of neurotransmitter secretion. Localizes to terminal bouton. Is expressed in epiphysis; photoreceptor cell; retinal cone cell; retinal inner plexiform layer; and retinal outer plexiform layer. Orthologous to human CPLX4 (complexin 4).
Genome Resources: Alliance (1),  Gene:768157 (1),  Ensembl(GRCz11):ENSDARG00000059978 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa14594 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44957 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-cplx4a N/A 2
    DISEASE ASSOCIATED WITH cplx4a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cplx4a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of neurotransmitter secretion (more)
    Cellular Component terminal bouton (more)
    Molecular Function syntaxin binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cplx4a-201 (1)    Ensembl 2514
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-cplx3/4 polyclonal Rabbit IHC, WB Synaptic Systems GmbH
    2
    Ab1-cplx4a polyclonal Rabbit IHC Synaptic Systems GmbH
    2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cplx4a No data available
    MARKER RELATIONSHIPS
    cplx4a Contained in: [BAC] CH211-233A1 (1)
    cplx4a Encodes: [cDNA] MGC:153429 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001077300 (1) 2321 nt
    Genomic GenBank:BX248399 (1) 158884 nt
    Select Tool
    Polypeptide UniProtKB:Q08BK6 (1) 159 aa
    Sequence Information (all 9)
    ORTHOLOGY for cplx4a ( Chr: 21 )
    CITATIONS (18)