Gene

elp1

ID
ZDB-GENE-071116-7
Name
elongator acetyltransferase complex subunit 1
Symbol
elp1 Nomenclature History
Previous Names
  • IKAP (1)
  • ikbkap
  • ikbkapl (1)
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to enable tRNA binding activity. Acts upstream of or within enteric nervous system development. Predicted to be located in cytoplasm and nucleus. Predicted to be part of elongator holoenzyme complex. Predicted to be active in cytosol. Is expressed in intestinal epithelium. Human ortholog(s) of this gene implicated in Riley-Day syndrome; asthma; and scoliosis. Orthologous to human ELP1 (elongator acetyltransferase complex subunit 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Cheng et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Cheng et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With elp1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
medulloblastoma Alliance Medulloblastoma 155255
Riley-Day syndrome Alliance Dysautonomia, familial 223900
Associated With elp1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR006849 Elongator complex protein 1
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Domain Details Per Protein
Protein Length Elongator complex protein 1 WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:E9QB69 1068
UniProtKB:A0A0R4IJ07 1311
UniProtKB:A0A0R4IKD3 158
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-ikbkap polyclonal IgG Rabbit
  • IHC
Santa Cruz Biotechnology, Inc.
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations