ZFIN ID: ZDB-GENE-071116-7
Gene Name: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
Gene Symbol: ikbkap
Previous Names: IKAP (1), ikbkapl (1)
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. 1 from Cheng et al., 2015
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  intestinal epithelium
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Targeting reagents: MO1-ikbkap (1), MO2-ikbkap (1)
PHENOTYPE
Data: 2 figures from Cheng et al., 2015
Observed in: enteric nervous system development, intestine enteric neuron, posterior intestine enteric neuron
DISEASE ASSOCIATED WITH ikbkap HUMAN ORTHOLOG 
Disease Ontology Term OMIM Term OMIM Phenotype ID
Riley-Day syndrome Dysautonomia, familial 223900
GENE ONTOLOGY 
Ontology GO Term
Biological Process enteric nervous system development (more)
Cellular Component Elongator holoenzyme complex (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR006849 (1)
  • InterPro:IPR015943 (1)
  • InterPro:IPR017986 (1)
  • Pfam:PF04762 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ikbkap-001 (1) 4151
    ncRNA ikbkap-002 (1) 714
    ikbkap-003 (1) 904
    aberrant processed transcript ikbkap-004 (1) 547
    GENE PRODUCT DESCRIPTION
    ANTIBODIES 
    Ab1-ikbkap (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ikbkap No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    ikbkapContained in: [BAC] DKEY-19K20 (order this), DKEY-124P11 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_684442 (1) 4167bp
    Genomic GenBank:FP103010 (1) 144426bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IJ07 (1) 1311aa
    Sequence Clusters UniGene:82379 (1)
    Sequence Information (all 10)
    OTHER ikbkap GENE PAGES 
  • Gene:561039 (1)
  • VEGA:OTTDARG00000041926 (1)
  • Ensembl(GRCz10):ENSDARG00000094204 (1)
  • ORTHOLOGY for ikbkap (Chr: 14) 
    Species Symbol Chromosome Accession # Evidence
    Human IKBKAP 9
  • Gene:8518
  • OMIM:603722
  • HGNC:5959
  • Amino acid sequence comparison (1)
    Mouse Ikbkap 4
  • MGI:1914544
  • Gene:230233
  • Amino acid sequence comparison (1)
    Download Curated Orthology
    CITATIONS (12)