ZFIN ID: ZDB-GENE-071116-7
Gene Name: elongator complex protein 1
Gene Symbol: elp1    Nomenclature History

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Previous Names: IKAP (1), ikbkap, ikbkapl (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have tRNA binding activity. Involved in enteric nervous system development. Predicted to localize to Elongator holoenzyme complex and cytosol. Is expressed in intestinal epithelium. Human ortholog(s) of this gene implicated in Riley-Day syndrome; asthma; and scoliosis. Orthologous to human ELP1 (elongator complex protein 1).
Genome Resources: Alliance (1),  Gene:561039 (1),  Ensembl(GRCz11):ENSDARG00000094204 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-elp1 N/A 1
MO2-elp1 N/A 1
DISEASE ASSOCIATED WITH elp1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Riley-Day syndrome Alliance Dysautonomia, familial 223900
DISEASE ASSOCIATED WITH elp1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process enteric nervous system development (more)
Cellular Component cytoplasm (more)
Molecular Function tRNA binding (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
aberrant processed transcript elp1-202 (1)    Ensembl 547
mRNA elp1-204 (1)    Ensembl 4151
ncRNA ikbkap-002 (1)    Ensembl 714
ikbkap-003 (1)    Ensembl 904
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-ikbkap polyclonal IgG Rabbit IHC Santa Cruz Biotechnology, Inc.
2
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM elp1 No data available
MARKER RELATIONSHIPS
elp1 Contained in: [BAC] DKEY-19K20 (order this), DKEY-124P11 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_684442 (1) 4165 nt
Genomic GenBank:FP103010 (1) 144426 nt
Select Tool
Polypeptide UniProtKB:A0A0R4IJ07 (1) 1311 aa
Sequence Information (all 10)
ORTHOLOGY for elp1 ( Chr: 14 )
CITATIONS (17)