Gene

cnot2

ID
ZDB-GENE-070410-70
Name
CCR4-NOT transcription complex, subunit 2
Symbol
cnot2 Nomenclature History
Previous Names
  • zgc:162316
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have poly(A)-specific ribonuclease activity. Predicted to be involved in negative regulation of translation; nuclear-transcribed mRNA poly(A) tail shortening; and regulation of stem cell population maintenance. Predicted to localize to CCR4-NOT core complex and P-body. Orthologous to human CNOT2 (CCR4-NOT transcription complex subunit 2).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cnot2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Intellectual developmental disorder with nasal speech, dysmorphic facies, and variable skeletal anomalies 618608
Associated With cnot2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR007282 NOT2/NOT3/NOT5, C-terminal
Family IPR040168 Not2/Not3/Not5
Homologous_superfamily IPR038635 CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily
Domain Details Per Protein
Protein Length CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily Not2/Not3/Not5 NOT2/NOT3/NOT5, C-terminal
UniProtKB:E9QCV7 173
UniProtKB:F1Q7P0 188
UniProtKB:E9QE21 110
UniProtKB:A4QN63 520
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations