Gene
cnot2
- ID
- ZDB-GENE-070410-70
- Name
- CCR4-NOT transcription complex, subunit 2
- Symbol
- cnot2 Nomenclature History
- Previous Names
-
- zgc:162316
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have poly(A)-specific ribonuclease activity. Predicted to be involved in negative regulation of translation; nuclear-transcribed mRNA poly(A) tail shortening; and regulation of stem cell population maintenance. Predicted to localize to CCR4-NOT core complex and P-body. Orthologous to human CNOT2 (CCR4-NOT transcription complex subunit 2).
- Genome Resources
- Note
- None
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
-
- GEO (1) Expression Atlas (1)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Intellectual developmental disorder with nasal speech, dysmorphic facies, and variable skeletal anomalies | 618608 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily | Not2/Not3/Not5 | NOT2/NOT3/NOT5, C-terminal |
|---|---|---|---|---|
|
UniProtKB:E9QCV7
|
173 | |||
|
UniProtKB:F1Q7P0
|
188 | |||
|
UniProtKB:E9QE21
|
110 | |||
|
UniProtKB:A4QN63
|
520 |
Interactions and Pathways
No data available
Plasmids
No data available