Gene

glrx2

ID
ZDB-GENE-040718-101
Name
glutaredoxin 2
Symbol
glrx2 Nomenclature History
Previous Names
  • grx2 (1)
  • zgc:92698
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Enables 2 iron, 2 sulfur cluster binding activity and glutathione disulfide oxidoreductase activity. Acts upstream of or within central nervous system development; circulatory system development; and protein deglutathionylation. Located in cytosol. Is expressed in neurons. Orthologous to human GLRX2 (glutaredoxin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With glrx2 Human Ortholog
No data available
Associated With glrx2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR011767 Glutaredoxin active site
Domain IPR002109 Glutaredoxin
Domain IPR011899 Glutaredoxin, eukaryotic/virial
Domain IPR014025 Glutaredoxin subgroup
Homologous_superfamily IPR036249 Thioredoxin-like superfamily
Domain Details Per Protein
Protein Length Glutaredoxin Glutaredoxin active site Glutaredoxin, eukaryotic/virial Glutaredoxin subgroup Thioredoxin-like superfamily
UniProtKB:A0A0R4IXU6 152
UniProtKB:A0A0R4IFC0 162
UniProtKB:Q6DH06 134
UniProtKB:A0A0R4ILJ8 170
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-glrx2 polyclonal Rabbit
  • IHC
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations