ZFIN ID: ZDB-GENE-040426-702
Gene Name: ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a
Gene Symbol: atp2a2a
Previous Names: atp2a2 (1), serca2 (1), zgc:55380 (1)
Location: Chr: 8 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 14 figures from 7 publications
Directly Submitted Expression Data: 7 figures (12 images) from Thisse et al., 2004 [MGC:55380]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7165932]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  atrium, cardiac ventricle, cephalic musculature, heart (all 14) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
sa13962 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-atp2a2a (1)
    PHENOTYPE
    Data: Fig. 4 from Ebert et al., 2005
    Observed in: atrium, cardiac ventricle, heart contraction, heart looping (all 6) expand
    DISEASE ASSOCIATED WITH atp2a2a HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    acrokeratosis verruciformis Acrokeratosis verruciformis 101900
    keratosis follicularis Darier disease 124200
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process heart looping (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function ATP binding (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001757 (1)
  • InterPro:IPR004014 (1)
  • InterPro:IPR005782 (1)
  • InterPro:IPR006068 (1)
  • InterPro:IPR008250 (1)
  • InterPro:IPR018303 (1)
  • InterPro:IPR023214 (1)
  • InterPro:IPR023298 (1)
  • InterPro:IPR023299 (1)
  • InterPro:IPR030327 (1)
  • PROSITE:PS00154 (1)
  • Pfam:PF00122 (1)
  • Pfam:PF00689 (1)
  • Pfam:PF00690 (1)
  • EC:3.6.3.8 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA atp2a2a-001 (1) 3724
    aberrant processed transcript atp2a2a-002 (1) 798
    mRNA atp2a2a-003 (1) 3186
    GENE PRODUCT DESCRIPTION
    ANTIBODIES 
    Ab1-atp2a2a (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM atp2a2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    atp2a2aContained in: [BAC] DKEY-252G21 (1) (order this)
    atp2a2aEncodes: [EST] IMAGE:7165932 (1) (order this)
    [cDNA] MGC:55380 (1) (order this), MGC:193107 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200965 (1) 3738bp
    Genomic GenBank:CR407563 (1) 109914bp
    Select Tool
    Polypeptide UniProtKB:A9C3Q4 (1) 1042aa
    Sequence Clusters UniGene:16838 (1)
    Sequence Information (all 23)
    OTHER atp2a2a GENE PAGES 
  • Gene:393940 (1)
  • VEGA:OTTDARG00000020112 (1)
  • Ensembl(GRCz10):ENSDARG00000029439 (1)
  • ORTHOLOGY for atp2a2a (Chr: 8) 
    Species Symbol Chromosome Accession # Evidence
    Human ATP2A2 12
  • Gene:488
  • OMIM:108740
  • HGNC:812
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Atp2a2 5
  • MGI:88110
  • Gene:11938
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (35)