ZFIN ID: ZDB-GENE-040426-702
Gene Name: ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a
Gene Symbol: atp2a2a
Previous Names: atp2a2 (1), serca2 (1), zgc:55380 (1)
Location: Chr: 8   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 12 figures from 5 publications
Directly Submitted Expression Data: 7 figures (12 images) from Thisse et al., 2004 [MGC:55380]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7165932]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  atrium, cardiac ventricle, cephalic musculature, heart (all 14) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
sa13962 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-atp2a2a (1)
    PHENOTYPE
    Data: Fig. 4 from Ebert et al., 2005
    Observed in: atrium, cardiac ventricle, heart contraction, heart looping (all 6) expand
    DISEASE ASSOCIATED WITH atp2a2a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    acrokeratosis verruciformis Acrokeratosis verruciformis 101900
    keratosis follicularis Darier disease 124200
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process heart looping (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function ATP binding (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001757 (1)
  • InterPro:IPR004014 (1)
  • InterPro:IPR005782 (1)
  • InterPro:IPR006068 (1)
  • InterPro:IPR008250 (1)
  • InterPro:IPR018303 (1)
  • InterPro:IPR023214 (1)
  • InterPro:IPR023298 (1)
  • InterPro:IPR023299 (1)
  • InterPro:IPR030332 (1)
  • PROSITE:PS00154 (1)
  • Pfam:PF00122 (1)
  • Pfam:PF00689 (1)
  • Pfam:PF00690 (1)
  • Pfam:PF00702 (1)
  • Pfam:PF08282 (1)
  • EC:3.6.3.8 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA atp2a2a-001 (1) 3724
    aberrant processed transcript atp2a2a-002 (1) 798
    mRNA atp2a2a-003 (1) 3186
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-atp2a2a (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM atp2a2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    atp2a2a Contained in: [BAC] DKEY-252G21 (1) (order this)
    atp2a2a Encodes: [EST] IMAGE:7165932 (1) (order this)
    [cDNA] MGC:55380 (1) (order this), MGC:193107 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200965 (1) 3738 bp
    Genomic GenBank:CR407563 (1) 109914 bp
    Select Tool
    Polypeptide UniProtKB:A9C3Q4 (1) 1042 aa
    Sequence Clusters UniGene:16838 (1)
    Sequence Information (all 23)
    OTHER atp2a2a GENE PAGES
  • Gene:393940 (1)
  • VEGA:OTTDARG00000020112 (1)
  • Ensembl(Zv9):ENSDARG00000029439 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish atp2a2a 8  
    Human ATP2A2 12 (12q24.11)
  • OMIM:108740
  • Gene:488
  • Mouse Atp2a2 5 ( 62.38 cM)
  • MGI:88110
  • Gene:11938
  • Orthology Details
    CITATIONS (30)