ZFIN ID: ZDB-GENE-040426-702
Gene Name: ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a
Gene Symbol: atp2a2a
Previous Names: atp2a2 (1), serca2 (1), zgc:55380 (1)
Location: Chr: 8   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 11 figures from 4 publications
Directly Submitted Expression Data: 7 figures (12 images) from Thisse et al., 2004 [MGC:55380]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7165932]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  atrium, cardiac ventricle, cephalic musculature, heart (all 14) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa13962
Knockdown reagents: MO1-atp2a2a (1)
PHENOTYPE
Data: Fig. 4 from Ebert et al., 2005
Observed in: atrium, cardiac ventricle, heart contraction, heart looping (all 6) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Acrokeratosis verruciformis 101900
Darier disease 124200
GENE ONTOLOGY
Ontology GO Term
Biological Process heart looping (more)
Cellular Component integral component of membrane (more)
Molecular Function ATP binding (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001757 (1)
  • InterPro:IPR004014 (1)
  • InterPro:IPR005782 (1)
  • InterPro:IPR006068 (1)
  • InterPro:IPR008250 (1)
  • InterPro:IPR018303 (1)
  • InterPro:IPR023214 (1)
  • InterPro:IPR023298 (1)
  • InterPro:IPR023299 (1)
  • PROSITE:PS00154 (1)
  • Pfam:PF00122 (1)
  • Pfam:PF00689 (1)
  • Pfam:PF00690 (1)
  • Pfam:PF00702 (1)
  • Pfam:PF08282 (1)
  • EC:3.6.3.8 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA atp2a2a-001 (1) 3724
    aberrant processed transcript atp2a2a-002 (1) 798
    mRNA atp2a2a-003 (1) 3186
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-atp2a2a (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM atp2a2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    atp2a2a Contained in: [BAC] DKEY-252G21 (1)
    atp2a2a Encodes: [EST] IMAGE:7165932 (1) (order this)
    [cDNA] MGC:55380 (1) (order this), MGC:193107 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200965 (1) 3738 bp
    Genomic GenBank:CR407563 (1) 109914 bp
    Select Tool
    Polypeptide UniProtKB:A9C3Q4 (1) 1042 aa
    Sequence Clusters UniGene:16838 (1)
    Sequence Information (all 23)
    OTHER atp2a2a GENE PAGES
  • Gene:393940 (1)
  • VEGA:OTTDARG00000020112 (1)
  • Ensembl(Zv9):ENSDARG00000029439 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish atp2a2a 8  
    Human ATP2A2 12 (12q24.11)
  • OMIM:108740
  • Gene:488
  • Mouse Atp2a2 5 ( 62.38 cM)
  • MGI:88110
  • Gene:11938
  • Orthology Details
    CITATIONS (25)