Gene

arl6ip1

ID
ZDB-GENE-040426-1087
Name
ADP-ribosylation factor-like 6 interacting protein 1
Symbol
arl6ip1 Nomenclature History
Previous Names
  • arl6ip (1)
  • zgc:56593 (1)
  • zgc:77873
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Involved in neural crest cell migration and retina morphogenesis in camera-type eye. Predicted to localize to Sec61 translocon complex and integral component of membrane. Is expressed in several structures, including blastodisc; central nervous system; hypochord; optic cup; and retina. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 61. Orthologous to human ARL6IP1 (ADP ribosylation factor like GTPase 6 interacting protein 1).
Genome Resources
Note
None
Expression
All Expression Data
5 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
20 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With arl6ip1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hereditary spastic paraplegia 61 Alliance ?Spastic paraplegia 61, autosomal recessive 615685
Associated With arl6ip1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR033301 ADP-ribosylation factor-like protein 6-interacting protein 1
Domain Details Per Protein
Protein Length ADP-ribosylation factor-like protein 6-interacting protein 1
UniProtKB:Q7ZWB4 203
UniProtKB:E9QGB6 160
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-arl6ip1 polyclonal IgG Rabbit
  • WB
Abcam plc
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations