ZFIN ID: ZDB-GENE-040407-2
Gene Name: ELOVL fatty acid elongase 5
Gene Symbol: elovl5    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name:

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Exhibits fatty acid elongase activity. Involved in fatty acid elongation, unsaturated fatty acid; long-chain fatty acid biosynthetic process; and very long-chain fatty acid biosynthetic process. Predicted to localize to integral component of endoplasmic reticulum membrane and integral component of plasma membrane. Is expressed in several structures, including blood; digestive system; fat cell; pleuroperitoneal region; and yolk syncytial layer. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 38. Orthologous to human ELOVL5 (ELOVL fatty acid elongase 5).
Genome Resources: Alliance (1),  Gene:393425 (1),  Ensembl(GRCz11):ENSDARG00000004979 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb333 Small Deletion Exon 5 Unknown CRISPR
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-elovl5 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH elovl5 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
spinocerebellar ataxia type 38 Alliance Spinocerebellar ataxia 38 615957
DISEASE ASSOCIATED WITH elovl5 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process fatty acid elongation (more)
Cellular Component integral component of plasma membrane (more)
Molecular Function fatty acid elongase activity (more)
GO Terms (all 26)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA elovl5-201 (1)    Ensembl 2206
elovl5-203 (1)    Ensembl 539
elovl5-204 (1)    Ensembl 833
ncRNA elovl5-004 (1)    Ensembl 677
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM elovl5 No data available
MARKER RELATIONSHIPS
elovl5 Contained in: [BAC] CH211-71K24 (1)
elovl5 Encodes: [cDNA] MGC:63549 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_200453 (1) 1907 nt
Genomic GenBank:CR376766 (1) 155126 nt
Select Tool
Polypeptide UniProtKB:Q8AX86 (1) 291 aa
Sequence Information (all 15)
ORTHOLOGY for elovl5 ( Chr: 13 )
CITATIONS (48)