Gene

tjp3

ID
ZDB-GENE-030828-10
Name
tight junction protein 3
Symbol
tjp3 Nomenclature History
Previous Names
  • cb766 (1)
  • wu:fj93c08
  • zo-3 (1)
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have cell adhesion molecule binding activity. Involved in multicellular organismal homeostasis and water homeostasis. Localizes to bicellular tight junction. Is expressed in several structures, including digestive system; integument; mesoderm; pleuroperitoneal region; and sensory system. Orthologous to human TJP3 (tight junction protein 3).
Genome Resources
Note
None
Expression
All Expression Data
17 figures from 4 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Kiener et al., 2008
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tjp3 Human Ortholog
No data available
Associated With tjp3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001452 SH3 domain
Domain IPR001478 PDZ domain
Domain IPR008144 Guanylate kinase-like domain
Domain IPR008145 Guanylate kinase/L-type calcium channel beta subunit
Family IPR005420 Tight junction protein ZO-3
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036028 SH3-like domain superfamily
Homologous_superfamily IPR036034 PDZ superfamily
Domain Details Per Protein
Protein Length Guanylate kinase-like domain Guanylate kinase/L-type calcium channel beta subunit PDZ domain PDZ superfamily P-loop containing nucleoside triphosphate hydrolase SH3 domain SH3-like domain superfamily Tight junction protein ZO-3
UniProtKB:E9QGL7 480
UniProtKB:E9QHG6 825
UniProtKB:F1R3X0 1255
UniProtKB:Q7ZV71 506
UniProtKB:F1QXZ7 294
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations