ZFIN ID: ZDB-GENE-030813-2
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.
Gene Name: piwi-like RNA-mediated gene silencing 1
Gene Symbol: piwil1
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: ziwi (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 8 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits piRNA binding activity; involved in several processes, including anatomical structure morphogenesis, gene silencing by RNA, and germ cell development; localizes to the P granule; orthologous  ...
GENE EXPRESSION
All Expression Data: 25 figures from 18 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh219 Point Mutation Unknown Premature Stop ENU
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • fh220 Point Mutation Unknown Unknown ENU
    fh221 Point Mutation Unknown Unknown ENU
    hu2410 Point Mutation Unknown Unknown ENU
    hu2479 Point Mutation Unknown Premature Stop ENU
    la016400Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • la026576Tg Transgenic Insertion Unknown Unknown DNA
    piwil1_unrecovered Point Mutation Unknown Unknown ENU
    sa7619 Point Mutation Unknown Missense ENU
    sa8531 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa30904 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa45333 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • PHENOTYPE
    Data: 2 figures from Houwing et al., 2007
    Observed in:
    DISEASE ASSOCIATED WITH piwil1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH piwil1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process anatomical structure morphogenesis (more)
    Cellular Component cytoplasm (more)
    Molecular Function piRNA binding (more)
    GO Terms (all 22)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003100 (1)
  • InterPro:IPR003165 (1)
  • InterPro:IPR012337 (1)
  • InterPro:IPR031320 (1)
  • InterPro:IPR031326 (1)
  • InterPro:IPR036085 (1)
  • InterPro:IPR036397 (1)
    		•
  • PROSITE:PS50821 (1)
  • PROSITE:PS50822 (1)
    		•
  • Pfam:PF02170 (1)
  • Pfam:PF02171 (1)
  • Pfam:PF05831 (1)
    		•
  • EC:3.1.26.- (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA piwil1-002 (1) 1465
    Select Tool
    piwil1-006 (1) 898
    Select Tool
    mRNA piwil1-203 (1) 549
    Select Tool
    piwil1-204 (1) 762
    Select Tool
    piwil1-205 (1) 3257
    Select Tool
    piwil1-206 (1) 915
    Select Tool
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM piwil1
    MARKER RELATIONSHIPS
    piwil1Contained in: [BAC] CH73-308B14 (1) (order this), DKEY-245G2 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_183338 (1) 3273bp
    Select Tool
    Genomic GenBank:CR450819 (1) 168244bp
    Select Tool
    Polypeptide UniProtKB:Q8UVX0 (1) 858aa
    Select Tool
    Sequence Clusters UniGene:83448 (1)
    Sequence Information (all 17)
    OTHER piwil1 GENE PAGES
  • Alliance (1)
  • Gene:368200 (1)
  • VEGA:OTTDARG00000020442 (1)
  • Ensembl(GRCz11):ENSDARG00000041699 (2)
    • ORTHOLOGY for piwil1 (Chr: 8)
    CITATIONS (81)