Gene
piwil1
- ID
- ZDB-GENE-030813-2
- Name
- piwi-like RNA-mediated gene silencing 1
- Symbol
- piwil1 Nomenclature History
- Previous Names
-
- ziwi (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Exhibits piRNA binding activity. Involved in several processes, including gene silencing by RNA; germ cell development; and piRNA metabolic process. Localizes to P granule. Is expressed in several structures, including blastodisc; central nervous system; eye; reproductive system; and unfertilized egg. Orthologous to several human genes including PIWIL1 (piwi like RNA-mediated gene silencing 1).
- Genome Resources
- Note
- None
- All Expression Data
- 29 figures from 21 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Houwing et al., 2007
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR003100 | PAZ domain |
Domain | IPR003165 | Piwi domain |
Domain | IPR031320 | GAGE |
Family | IPR031326 | Piwi-like protein 1 |
Homologous_superfamily | IPR012337 | Ribonuclease H-like superfamily |
Homologous_superfamily | IPR036085 | PAZ domain superfamily |
Homologous_superfamily | IPR036397 | Ribonuclease H superfamily |
Domain Details Per Protein
Protein | Length | GAGE | PAZ domain | PAZ domain superfamily | Piwi domain | Piwi-like protein 1 | Ribonuclease H-like superfamily | Ribonuclease H superfamily |
---|---|---|---|---|---|---|---|---|
UniProtKB:A0A0J9YJF9
|
171 | |||||||
UniProtKB:A0A0R4IWH9
|
143 | |||||||
UniProtKB:Q8UVX0
|
858 | |||||||
UniProtKB:E9QHH1
|
230 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
piwil1-203
(1)
|
549 nt | |
mRNA |
piwil1-204
(1)
|
762 nt | |
mRNA |
piwil1-205
(1)
|
3257 nt | |
mRNA |
piwil1-206
(1)
|
915 nt | |
ncRNA |
piwil1-006
(1)
|
898 nt |
Interactions and Pathways
No data available
Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
---|---|---|---|---|---|---|---|
Ab2-piwil1 | polyclonal | Rabbit |
|
1 | |||
AB4-piwil1 | polyclonal | Rabbit |
|
1 | |||
Ab1-piwil1 | polyclonal | Rabbit |
|
6 |
Plasmids
No data available
- Gene Tree
- Ensembl