Gene

adka

ID
ZDB-GENE-030425-3
Name
adenosine kinase a
Symbol
adka Nomenclature History
Previous Names
  • adk (1)
  • cb163 (1)
  • wu:fb39g06
  • wu:fb57c05
  • wu:fc10c08
  • wu:fc41g07
  • wu:fi37c12
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have adenosine kinase activity. Predicted to be involved in AMP salvage; phosphorylation; and purine ribonucleoside salvage. Predicted to localize to cytosol and nucleus. Is expressed in several structures, including digestive system; fin; immature eye; nervous system; and periderm. Human ortholog(s) of this gene implicated in hypermethioninemia due to adenosine kinase deficiency. Orthologous to human ADK (adenosine kinase).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adka Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hypermethioninemia due to adenosine kinase deficiency Alliance Hypermethioninemia due to adenosine kinase deficiency 614300
Associated With adka Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR002173 Carbohydrate/purine kinase, PfkB, conserved site
Domain IPR011611 Carbohydrate kinase PfkB
Family IPR001805 Adenosine kinase
Homologous_superfamily IPR029056 Ribokinase-like
Domain Details Per Protein
Protein Length Adenosine kinase Carbohydrate kinase PfkB Carbohydrate/purine kinase, PfkB, conserved site Ribokinase-like
UniProtKB:A0A2R8Q0N1 334
UniProtKB:Q803H6 334
UniProtKB:A0A0R4IYX1 345
UniProtKB:Q6P3J9 359
UniProtKB:B8JIM5 131
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations