header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-7828
Gene Name: lysine (K)-specific demethylase 1a
Gene Symbol: kdm1a
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: kdm1, aof2, lsd1 (1), wu:fb82e06, wu:fc51a02, wu:fj36a05, wu:fj66b06

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have several functions, including chromatin binding activity, flavin adenine dinucleotide binding activity, and histone demethylase activity (H3-dimethyl-K4 specific); involved in  ...
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
it627 Point Mutation Exon 17 Premature Stop ENU
sa23095 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa28869 Point Mutation Unknown Unknown ENU
    sa36433 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42949 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH kdm1a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Cleft palate, psychomotor retardation, and distinctive facial features 616728
    DISEASE ASSOCIATED WITH kdm1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of retinoic acid biosynthetic process (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 14)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA kdm1a-005 (1) 975
    kdm1a-006 (1) 1015
    mRNA kdm1a-201 (1) 3367
    kdm1a-202 (1) 887
    kdm1a-203 (1) 500
    kdm1a-204 (1) 456
    kdm1a-207 (1) 606
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM kdm1a No data available
    MARKER RELATIONSHIPS
    kdm1aContained in: [BAC] DKEY-265G24 (1) (order this)
    kdm1aEncodes: [EST] fb82e06, fc51a02, fj36a05, fj66b06
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001242995 (1)
    Genomic GenBank:AL844186 (1) 221158bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A2R8Q8P2 (1) 858aa
    Sequence Clusters UniGene:105968 (1)
    Sequence Information (all 32)
    ORTHOLOGY for kdm1a (Chr: 17)
    CITATIONS (26)