ZFIN ID: ZDB-GENE-030131-6022
Gene Name: integrin, beta 5
Gene Symbol: itgb5    Nomenclature History

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Previous Name: wu:fi30h12

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have integrin binding activity. Predicted to be involved in several processes, including cell adhesion mediated by integrin; cell-matrix adhesion; and integrin-mediated signaling pathway. Predicted to localize to cell surface; focal adhesion; and integrin complex. Is expressed in margin. Orthologous to human ITGB5 (integrin subunit beta 5).
Genome Resources: Alliance (1),  Gene:563556 (1),  Ensembl(GRCz11):ENSDARG00000012942 (1)
GENE EXPRESSION
All Expression Data: Fig. 4 from Ablooglu et al., 2010
Wild-type Stages, Structures: Gastrula:75%-epiboly (8.0h-9.0h) to Gastrula:75%-epiboly (8.0h-9.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026818Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11845 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH itgb5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH itgb5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell adhesion (more)
    Cellular Component integral component of membrane (more)
    Molecular Function signaling receptor activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA itgb5-203 (1)    Ensembl 767
    itgb5-204 (1)    Ensembl 3427
    ncRNA itgb5-003 (1)    Ensembl 375
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM itgb5 No data available
    MARKER RELATIONSHIPS
    itgb5 Contained in: [BAC] DKEY-16N5 (1) (order this), DKEY-16P7 (1) (order this), DKEY-89P3 (1) (order this)
    itgb5 Contains: [SNP] rs3728219 (1), rs3728220 (1), rs3728221 (1), rs3728222 (1), rs3728223 (1)
    itgb5 Encodes: [EST] fi30h12
    [cDNA] MGC:163102 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001082836 (1) 3363 nt
    Genomic GenBank:CR391905 (1) 221511 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1QF91 (1) 823 aa
    Sequence Information (all 22)
    ORTHOLOGY for itgb5 ( Chr: 9 )
    CITATIONS (32)