Gene

nf1a

ID
ZDB-GENE-030131-4907
Name
neurofibromin 1a
Symbol
nf1a Nomenclature History
Previous Names
  • nf1 (2)
  • fe06d03
  • hm:zehn0874 (1)
  • wu:fe06d03
  • zehn0874
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Involved in several processes, including circulatory system development; learning or memory; and neurogenesis. Is expressed in blood vasculature; dorsal aorta; head; heart; and spinal cord. Human ortholog(s) of this gene implicated in autistic disorder; central nervous system cancer (multiple); hematologic cancer (multiple); neurofibromatosis 1; and neurofibromatosis-Noonan syndrome. Orthologous to human NF1 (neurofibromin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
9 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nf1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
juvenile myelomonocytic leukemia Alliance Leukemia, juvenile myelomonocytic 607785
neurofibromatosis 1 Alliance Neurofibromatosis, type 1 162200
neurofibromatosis-Noonan syndrome Alliance Neurofibromatosis-Noonan syndrome 601321
spinal neurofibromatosis Alliance Neurofibromatosis, familial spinal 162210
Watson syndrome Alliance Watson syndrome 193520
Associated With nf1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-nf1 polyclonal IgG Rabbit
  • WB
Abcam plc
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations