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ZIRC
ZFIN ID: ZDB-GENE-091111-4
Gene Name: neurofibromin 1b
Gene Symbol: nf1b
Sequence Ontology ID : SO:0001217

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Previous Name: si:dkey-15g19.1

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(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Involved in several processes, including circulatory system development; learning or memory; and neurogenesis. Human ortholog(s) of this gene implicated in autistic disorder; hematologic cancer  ...
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Larval:Day 4 (96.0h-120.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
p303 Indel Exon 17 Premature Stop ZINC_FINGER_NUCLEASE
p304 Indel Exon 17 Premature Stop ZINC_FINGER_NUCLEASE
sa16515 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21786 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa27657 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa27658 Point Mutation Unknown Premature Stop ENU
    sa34960 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41713 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH nf1b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    juvenile myelomonocytic leukemia Leukemia, juvenile myelomonocytic 607785
    neurofibromatosis Neurofibromatosis, familial spinal 162210
    neurofibromatosis 1 Neurofibromatosis, familial spinal 162210
    Neurofibromatosis, type 1 162200
    Neurofibromatosis-Noonan syndrome 601321
    Watson syndrome 193520
    DISEASE ASSOCIATED WITH nf1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process blood vessel development (more)
    GO Terms (all 10)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nf1b-201 (1) 8675
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nf1b No data available
    MARKER RELATIONSHIPS
    nf1b Contained in: [BAC] CH73-19D19 (1) (order this), DKEY-15G19 (1) (order this), DKEY-174L22 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005169189 (1) 9061 bp
    Genomic GenBank:CT573181 (1) 143897 bp
    Select Tool
    Polypeptide UniProtKB:E7FFY1 (1) 2759 aa
    Sequence Clusters UniGene:157224 (1)
    Sequence Information (all 12)
    ORTHOLOGY for nf1b ( Chr: 10 )
    CITATIONS (29)