Gene

trpm7

ID
ZDB-GENE-021115-2
Name
transient receptor potential cation channel, subfamily M, member 7
Symbol
trpm7 Nomenclature History
Previous Names
  • cb495 (1)
  • nutria (1)
  • tct
  • touchtone
  • transient receptor potential melastatin 7 (1)
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have calcium channel activity. Involved in several processes, including exocrine pancreas development; magnesium ion homeostasis; and melanocyte differentiation. Localizes to integral component of plasma membrane. Is expressed in several structures, including digestive system; immature eye; integument; nervous system; and renal system. Used to study sinoatrial node disease. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis-parkinsonism/dementia complex 1. Orthologous to human TRPM7 (transient receptor potential cation channel subfamily M member 7).
Genome Resources
Note
None
Expression
All Expression Data
51 figures from 28 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
30 figures from 10 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With trpm7 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 Alliance {Amyotrophic lateral sclerosis-parkinsonism/dementia complex, susceptibility to} 105500
Associated With trpm7 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004166 MHCK/EF2 kinase
Domain IPR005821 Ion transport domain
Domain IPR032415 TRPM, tetramerisation domain
Domain IPR041491 TRPM, SLOG domain
Family IPR029594 Transient receptor potential cation channel subfamily M member 2
Family IPR029601 Transient receptor potential cation channel subfamily M member 7
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR037162 TRPM, tetramerisation domain superfamily
Domain Details Per Protein
Protein Length Ion transport domain MHCK/EF2 kinase Protein kinase-like domain superfamily Transient receptor potential cation channel subfamily M member 2 Transient receptor potential cation channel subfamily M member 7 TRPM, SLOG domain TRPM, tetramerisation domain TRPM, tetramerisation domain superfamily
UniProtKB:A0A2R8PXP3 1787
UniProtKB:F8W4J6 209
UniProtKB:S5UFQ9 1774
UniProtKB:F8W297 606
UniProtKB:A0A2R8Q252 1772
UniProtKB:Q563W7 1774
UniProtKB:B3DK48 1789
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations