ZFIN ID: ZDB-GENE-021115-2
Gene Name: transient receptor potential cation channel, subfamily M, member 7
Gene Symbol: trpm7
Sequence Ontology ID : SO:0000704

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Previous Names: cb495 (1), nutria (1), tct, touchtone, transient receptor potential melastatin 7 (1)

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(Including Attributions)
Location: Chr: 18 Mapping Details/Browsers
AUTOMATED DESCRIPTION
Predicted to have ATP binding activity, calcium activated cation channel activity, and protein serine/threonine kinase activity; involved in several processes, including divalent metal ion transport,  ...
GENE EXPRESSION
All Expression Data: 45 figures from 25 publications
Directly Submitted Expression Data: 5 figures (20 images) from Thisse et al., 2001 [cb495]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
b508 Small Deletion Unknown Frameshift, Premature Stop ENU
b722 Unknown Unknown Unknown ENU
j124e1 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • j124e2 Unknown Unknown Unknown ENU
    la013193Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • mi174 Point Mutation Unknown Premature Stop ENU
    os1 Unknown Unknown Unknown
    os2 Unknown Unknown Unknown
    sa36550 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39184 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tz310c Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 30 figures from 10 publications
    Observed in:
    DISEASE ASSOCIATED WITH trpm7 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    {Amyotrophic lateral sclerosis-parkinsonism/dementia complex, susceptibility to} 105500
    DISEASE ASSOCIATED WITH trpm7 VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    sinoatrial node disease WT + MO3-trpm7 standard conditions Sah et al., 2013
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process divalent metal ion transport (more)
    Cellular Component integral component of plasma membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 29)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004166 (1)
  • InterPro:IPR005821 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR029577 (1)
  • InterPro:IPR029601 (1)
  • InterPro:IPR032415 (1)
  • InterPro:IPR037162 (1)
  • InterPro:IPR041491 (1)
  • PROSITE:PS51158 (1)
  • Pfam:PF00520 (1)
  • Pfam:PF02816 (1)
  • Pfam:PF16519 (1)
  • Pfam:PF18139 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA trpm7-003 (1) 514
    mRNA trpm7-201 (1) 2499
    trpm7-203 (1) 625
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM trpm7
    MARKER RELATIONSHIPS
    trpm7Contained in: [Fosmid] CH1073-401P22 (1) (order this)
    trpm7Encodes: [EST] cb495 (1) (order this)
    [cDNA] MGC:194798 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001030061 (1) 6259bp
    Genomic GenBank:CU928201 (1) 34876bp
    Select Tool
    Polypeptide UniProtKB:B3DK48 (1) 1789aa
    Sequence Clusters UniGene:2991 (1)
    Sequence Information (all 29)
    OTHER trpm7 GENE PAGES
  • Alliance (1)
  • Gene:280653 (1)
  • VEGA:OTTDARG00000034671 (1)
  • Ensembl(GRCz11):ENSDARG00000036232 (2)
  • ORTHOLOGY for trpm7 (Chr: 18)
    CITATIONS (71)