Gene

trpm7

ID
ZDB-GENE-021115-2
Name
transient receptor potential cation channel, subfamily M, member 7
Symbol
trpm7 Nomenclature History
Previous Names
  • cb495 (1)
  • nutria (1)
  • tct
  • touchtone
  • transient receptor potential melastatin 7 (1)
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have calcium channel activity. Involved in several processes, including exocrine pancreas development; magnesium ion homeostasis; and melanocyte differentiation. Localizes to integral component of plasma membrane. Is expressed in several structures, including digestive system; immature eye; integument; nervous system; and renal system. Used to study sinoatrial node disease. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis-parkinsonism/dementia complex 1. Orthologous to human TRPM7 (transient receptor potential cation channel subfamily M member 7).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
51 figures from 28 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
30 figures from 10 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With trpm7 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 Alliance {Amyotrophic lateral sclerosis-parkinsonism/dementia complex, susceptibility to} 105500
Associated With trpm7 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004166 MHCK/EF2 kinase
Domain IPR005821 Ion transport domain
Domain IPR032415 TRPM, tetramerisation domain
Domain IPR041491 TRPM, SLOG domain
Family IPR029601 Transient receptor potential cation channel subfamily M member 7
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR037162 TRPM, tetramerisation domain superfamily
Domain Details Per Protein
Protein Length Ion transport domain MHCK/EF2 kinase Protein kinase-like domain superfamily Transient receptor potential cation channel subfamily M member 7 TRPM, SLOG domain TRPM, tetramerisation domain TRPM, tetramerisation domain superfamily
UniProtKB:F8W297 606
UniProtKB:Q563W7 1774
UniProtKB:A0A2R8PXP3 1787
UniProtKB:F8W4J6 209
UniProtKB:A0A2R8Q252 1772
UniProtKB:S5UFQ9 1774
UniProtKB:B3DK48 1789
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations