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General Information
ZIRC
ZFIN ID: ZDB-GENE-010606-1
Gene Name: cadherin 1, type 1, E-cadherin (epithelial)
Gene Symbol: cdh1
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: E-cadherin (1), hab, half baked

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits G-protein alpha-subunit binding activity. Involved in several processes, including adherens junction maintenance; embryonic morphogenesis; and germ cell migration. Localizes to several  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
dtv43 Point Mutation Unknown Missense ENU
la011658Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • rk3 Point Mutation Intron 1 Splice Site, Premature Stop ENU
    sa41032 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tm94 Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ts18 Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tx230 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • vu44 Point Mutation Unknown Premature Stop
    xt17Tg Transgenic Insertion Unknown Unknown DNA_AND_CRISPR
    xt18Tg Transgenic Insertion Unknown Unknown DNA_AND_CRISPR
    Targeting reagents:
    DISEASE ASSOCIATED WITH cdh1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    blepharocheilodontic syndrome 1 Blepharocheilodontic syndrome 1 119580
    breast cancer {Breast cancer, lobular} 114480
    endometrial cancer Endometrial carcinoma, somatic 608089
    ovarian cancer Ovarian cancer, somatic 167000
    prostate cancer {Prostate cancer, susceptibility to} 176807
    stomach cancer Gastric cancer, hereditary diffuse, with or without cleft lip and/or palate 137215
    DISEASE ASSOCIATED WITH cdh1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell-cell adhesion (more)
    Cellular Component catenin complex (more)
    Molecular Function G-protein alpha-subunit binding (more)
    GO Terms (all 32)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cdh1-201 (1) 2494
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    MARKER RELATIONSHIPS
    cdh1Contained in: [BAC] CH73-289B2 (1) (order this), DKEY-173L11 (1) (order this)
    [Fosmid] CH1073-125P9 (1) (order this)
    cdh1Encodes: [EST] eu736 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131820 (1) 3340bp
    Genomic GenBank:BX322631 (1) 161710bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IFF8 (1) 877aa
    Sequence Clusters UniGene:78411 (1)
    Sequence Information (all 21)
    ORTHOLOGY for cdh1 (Chr: 7)
    CITATIONS (123)