ZFIN ID: ZDB-GENE-000607-83
Gene Name: keratin 4
Gene Symbol: krt4
Sequence Ontology ID : SO:0000704

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Previous Names: krt8 (1), cb59 (1), cytokeratin (1), etID20321.6 (1), wu:fa91a11, wu:fd19e09 (1), wu:fl23c09 (1), zf-K8 (1)

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(Including Attributions)
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have structural molecule activity; predicted to localize to the keratin filament; orthologous to several human genes including KRT8 (keratin 8).
GENE EXPRESSION
All Expression Data: 36 figures from 17 publications
Directly Submitted Expression Data: 6 figures (7 images) from Thisse et al., 2001 [cb59]
  12 figures (20 images) from Rauch et al., 2003 [cegs956]
Wild-type Stages, Structures: Cleavage:64-cell (2.0h-2.25h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa38567 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45260 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH krt4 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH krt4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component intermediate filament (more)
    Molecular Function structural molecule activity (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001664 (1)
  • InterPro:IPR003054 (1)
  • InterPro:IPR018039 (1)
  • InterPro:IPR032444 (1)
  • InterPro:IPR039008 (1)
  • PROSITE:PS00226 (1)
  • PROSITE:PS51842 (1)
  • Pfam:PF00038 (1)
  • Pfam:PF16208 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA krt4-201 (1) 2469
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM krt4
    MARKER RELATIONSHIPS
    krt4Contained in: [BAC] DKEY-195M11 (1) (order this)
    krt4Encodes: [EST] cb59 (1) (order this), cegs956 (1) (order this), fa91a11, fd19e09 (1), fl23c09 (1)
    [cDNA] MGC:76893 (1) (order this), MGC:174788 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131509 (1) 2480bp
    Genomic GenBank:CR753817 (1) 236737bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q9PV92 (1) 498aa
    Sequence Clusters UniGene:75111 (1)
    Sequence Information (all 34)
    OTHER krt4 GENE PAGES
  • Alliance (1)
  • Gene:794486 (1)
  • VEGA:OTTDARG00000019886 (1)
  • ORTHOLOGY for krt4 (Chr: 6)
    CITATIONS (109)