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Fig. 4

ID

ZDB-FIG-221222-30

Publication

Terai et al., 2021 - Electrophysiological and pharmacological characterization of spreading depolarization in the adult zebrafish tectum

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Fig. 4

Figure 4.An N-methyl-d-aspartate (NMDA) receptor antagonist attenuated spreading depolarization (SD) propagation in the zebrafish tectum. A: a schematic of the experimental process used to assess the effect of MK-801 (NMDA receptor antagonist) on SD in the zebrafish tectum. Representative traces of direct current (DC) potentials at the proximal (Rec1, solid lines) and distal (Rec2, dashed lines) electrodes in the optic tectum of the zebrafish pretreated with vehicle (B) and MK-801 (C). Bar graphs with dot-whisker plots of SD velocity (D), amplitude (E), and duration (F) observed in zebrafish pretreated with vehicle (n = 8) and MK-801 (n = 4). *P < 0.05. NS, not significant.

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Neurophysiol.