FIGURE
Fig. 3
- ID
- ZDB-FIG-211011-18
- Publication
- Wobus et al., 2021 - Luspatercept restores SDF-1-mediated hematopoietic support by MDS-derived mesenchymal stromal cells
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Fig. 3
A Representative images of zebrafish larvae at 48 hpi. Addition of RAP-536 to GDF-11 pre-treatment of co-cultured MSCs rescued the survival and homing of HSPCs in the CHT region. Surviving HSPCs (magenta) are indicated by white arrowheads, the vasculature is labeled in green. Scale bar 500 µm. B Quantification of HSPCs in the tail region at 48 hpi. One representative experiment is shown, N = 20 embryos in each group, **p < 0.01, ****p < 0.0001. Significance was assessed with Kruskal–Wallis test followed by Dunn’s multiple comparisons post-hoc test. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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