FIGURE

Figure 1

ID

ZDB-FIG-201229-77

Publication

Candiani et al., 2020 - Alexander Disease Modeling in Zebrafish: An In Vivo System Suitable to Perform Drug Screening

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Figure 1

GFP expression in transgenic glial fibrillary acid protein (GFAP) wildtype (WT) and GFAP R239C embryos. (A,B) The expression of GFAP WT-GFP protein is visible along the neural tube, with very few GFAP aggregates observed. (C) High magnification of embryo in (B) shows GFAP WT protein as filamentous structures. (D–F) Several aggregates of p.R239C in the brain and along the neural tube are found. Magnification: 4× (A,D); 10× (B,E); 20× (C,F). High magnification are shown by rectangular shape.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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