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General Information
ZIRC
ZFIN ID: ZDB-FIG-190221-2
Gerri et al., 2018 - Hif-1α and Hif-2α regulate hemogenic endothelium and hematopoietic stem cell formation in zebrafish. Blood   131(9):963-973 Full text @ Blood
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage: Prim-25
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage: Prim-25

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP s896Tg; zf169Tg control Prim-25 hematopoietic stem cell IFL
Prim-25 ventral wall of dorsal aorta hematopoietic cell IFL
s896Tg; zf169Tg + MO1-epas1a + MO3-epas1b standard conditions Prim-25 hematopoietic stem cell IFL
Prim-25 ventral wall of dorsal aorta hematopoietic cell IFL
s896Tg; zf169Tg + MO1-hif1aa + MO1-hif1ab standard conditions Prim-25 hematopoietic stem cell IFL
Prim-25 ventral wall of dorsal aorta hematopoietic cell IFL
mCherry s896Tg; zf169Tg control Prim-25 hematopoietic stem cell IFL
Prim-25 ventral wall of dorsal aorta hematopoietic cell IFL
s896Tg; zf169Tg + MO1-epas1a + MO3-epas1b standard conditions Prim-25 hematopoietic stem cell IFL
Prim-25 ventral wall of dorsal aorta hematopoietic cell IFL
s896Tg; zf169Tg + MO1-hif1aa + MO1-hif1ab standard conditions Prim-25 hematopoietic stem cell IFL
Prim-25 ventral wall of dorsal aorta hematopoietic cell IFL
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
s896Tg; zf169Tg + MO1-epas1a + MO3-epas1b standard conditions Prim-25 hematopoietic stem cell decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta hematopoietic cell decreased amount, abnormal
s896Tg; zf169Tg + MO1-hif1aa + MO1-hif1ab standard conditions Prim-25 hematopoietic stem cell decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta hematopoietic cell decreased amount, abnormal
Full text @ Blood