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ZIRC
ZFIN ID: ZDB-FIG-190221-4
Gerri et al., 2018 - Hif-1α and Hif-2α regulate hemogenic endothelium and hematopoietic stem cell formation in zebrafish. Blood   131(9):963-973 Full text @ Blood
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Knockdown Reagents:
Anatomical Terms:
Stage: Prim-25
PHENOTYPE:
Fish:
Condition:
Knockdown Reagents:
Observed In:
Stage: Prim-25

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
myb epas1abns231/bns231 ; epas1bbns232/bns232 standard conditions Prim-25 whole organism RTPCR
hif1aabns89/bns89; hif1abbns90/bns90 control Prim-25 ventral wall of dorsal aorta ISH
hif1aabns89/bns89; hif1abbns90/bns90 standard conditions Prim-25 whole organism RTPCR
hif1aabns89/bns89; hif1abbns90/bns90 hypoxia Prim-25 ventral wall of dorsal aorta ISH
hif1aabns89/bns89; hif1abbns90/bns90 + MO1-epas1a + MO3-epas1b control Prim-25 ventral wall of dorsal aorta ISH
hif1aabns89/bns89; hif1abbns90/bns90 + MO1-epas1a + MO3-epas1b standard conditions Prim-25 whole organism RTPCR
hif1aabns89/bns89; hif1abbns90/bns90 + MO1-epas1a + MO3-epas1b hypoxia Prim-25 ventral wall of dorsal aorta ISH
runx1 epas1abns231/bns231 ; epas1bbns232/bns232 standard conditions Prim-25 whole organism RTPCR
hif1aabns89/bns89; hif1abbns90/bns90 control Prim-25 ventral wall of dorsal aorta ISH
hif1aabns89/bns89; hif1abbns90/bns90 standard conditions Prim-25 whole organism RTPCR
hif1aabns89/bns89; hif1abbns90/bns90 hypoxia Prim-25 ventral wall of dorsal aorta ISH
hif1aabns89/bns89; hif1abbns90/bns90 + MO1-epas1a + MO3-epas1b control Prim-25 ventral wall of dorsal aorta ISH
hif1aabns89/bns89; hif1abbns90/bns90 + MO1-epas1a + MO3-epas1b standard conditions Prim-25 whole organism RTPCR
hif1aabns89/bns89; hif1abbns90/bns90 + MO1-epas1a + MO3-epas1b hypoxia Prim-25 ventral wall of dorsal aorta ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
epas1abns231/bns231 ; epas1bbns232/bns232 standard conditions Prim-25 whole organism runx1 expression decreased amount, abnormal
Prim-25 whole organism myb expression decreased amount, abnormal
hif1aabns89/bns89; hif1abbns90/bns90 control Prim-25 ventral wall of dorsal aorta runx1 expression decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta myb expression decreased amount, abnormal
hif1aabns89/bns89; hif1abbns90/bns90 standard conditions Prim-25 whole organism runx1 expression decreased amount, abnormal
Prim-25 whole organism myb expression decreased amount, abnormal
hif1aabns89/bns89; hif1abbns90/bns90 hypoxia Prim-25 ventral wall of dorsal aorta myb expression amount, ameliorated
Prim-25 ventral wall of dorsal aorta runx1 expression amount, ameliorated
hif1aabns89/bns89; hif1abbns90/bns90 + MO1-epas1a + MO3-epas1b control Prim-25 ventral wall of dorsal aorta myb expression decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta runx1 expression decreased amount, abnormal
hif1aabns89/bns89; hif1abbns90/bns90 + MO1-epas1a + MO3-epas1b standard conditions Prim-25 whole organism runx1 expression decreased amount, abnormal
Prim-25 whole organism myb expression decreased amount, abnormal
hif1aabns89/bns89; hif1abbns90/bns90 + MO1-epas1a + MO3-epas1b hypoxia Prim-25 ventral wall of dorsal aorta myb expression decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta runx1 expression decreased amount, abnormal
Full text @ Blood