ZFIN Figure: Zhao et al., 2017, Fig. 1

ZFIN ID: ZDB-FIG-181025-25

ZFIN ID: ZDB-FIG-181025-25

Zhao et al., 2017 - Irf8 regulates the progression of myeloproliferative neoplasm (MPN)-like syndrome via Mertk signaling in zebrafish. Leukemia 32(1):149-158 Full text @ Leukemia

ADDITIONAL FIGURES

EXPRESSION / LABELING:

Genes:	cebp1 cebpa mpx spi1b
Fish:	AB irf8^cq47/cq47 (AB)
Anatomical Terms:	common myeloid progenitor neutrophil
Stage Range:	Protruding-mouth to Day 6

PHENOTYPE:

Fish:	irf8^cq47/cq47 (AB)
Observed In:	common myeloid progenitor myeloid cell cell population proliferation neutrophil
Stage Range:	Protruding-mouth to Day 6

Fig. 1 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details

Gene	Fish	Conditions	Stage	Anatomy	Assay
cebp1	AB	standard conditions	Protruding-mouth	common myeloid progenitor	ISH
	irf8^cq47/cq47 (AB)	standard conditions	Protruding-mouth	common myeloid progenitor	ISH
cebpa	AB	standard conditions	Protruding-mouth	common myeloid progenitor	ISH
	irf8^cq47/cq47 (AB)	standard conditions	Protruding-mouth	common myeloid progenitor	ISH
mpx	AB	standard conditions	Day 6	neutrophil	ISH
	irf8^cq47/cq47 (AB)	standard conditions	Day 6	neutrophil	ISH
spi1b	AB	standard conditions	Protruding-mouth	common myeloid progenitor	ISH
	irf8^cq47/cq47 (AB)	standard conditions	Protruding-mouth	common myeloid progenitor	ISH

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
irf8^cq47/cq47 (AB)	standard conditions	Protruding-mouth	common myeloid progenitor cebp1 expression increased amount, abnormal
		Protruding-mouth	common myeloid progenitor cebp1 expression increased distribution, abnormal
		Protruding-mouth	common myeloid progenitor cebpa expression increased amount, abnormal
		Protruding-mouth	common myeloid progenitor cebpa expression increased distribution, abnormal
		Protruding-mouth	common myeloid progenitor spi1b expression increased amount, abnormal
		Protruding-mouth	common myeloid progenitor spi1b expression increased distribution, abnormal
		Protruding-mouth	myeloid cell cell population proliferation increased occurrence, abnormal
		Day 6	neutrophil mpx expression increased amount, abnormal
		Day 6	neutrophil mpx expression increased distribution, abnormal

Full text @ Leukemia