ZFIN ID: ZDB-FIG-171121-1
DeRossi et al., 2017 - MPI depletion enhances O-GlcNAcylation of p53 and suppresses the Warburg effect. eLIFE   6 Full text @ Elife
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Antibodies:
Fish:
Conditions:
Knockdown Reagents:
Anatomical Term:
Stage Range: Prim-5 to Day 4
PHENOTYPE:
Fish:
Conditions:
Knockdown Reagents:
Observed In:
Stage Range: Prim-5 to Day 4

Fig. 7 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
tp53 AB control Prim-5 whole organism WB
Day 4 whole organism WB
AB chemical treatment: OSMI-1 Day 4 whole organism WB
AB + MO1-mpi control Day 4 whole organism WB
AB + MO1-mpi standard conditions Prim-5 whole organism WB
AB + MO1-mpi chemical treatment: OSMI-1 Day 4 whole organism WB
AB + MO1-mpi + MO1-ogt.1 standard conditions Prim-5 whole organism WB
Day 4 whole organism WB
AB + MO1-ogt.1 standard conditions Day 4 whole organism WB
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-O-GlcNAc WB AB control Prim-5 whole organism
WB Day 4 whole organism
WB AB chemical treatment: 6-diazo-5-oxo-L-norleucine Day 4 whole organism
WB AB + MO1-mpi control Day 4 whole organism
WB AB + MO1-mpi standard conditions Prim-5 whole organism
WB AB + MO1-mpi chemical treatment: 6-diazo-5-oxo-L-norleucine Day 4 whole organism
WB AB + MO1-mpi + MO1-ogt.1 standard conditions Prim-5 whole organism
Ab2-ogt WB AB control Day 4 whole organism
WB AB chemical treatment: OSMI-1 Day 4 whole organism
WB AB + MO1-mpi control Day 4 whole organism
WB AB + MO1-mpi chemical treatment: OSMI-1 Day 4 whole organism
WB AB + MO1-mpi + MO1-ogt.1 control Day 4 whole organism
WB AB + MO1-ogt.1 control Day 4 whole organism
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO1-mpi control Day 4 whole organism Ab2-ogt labeling increased amount, abnormal
Day 4 whole organism Ab1-O-GlcNAc labeling increased amount, abnormal
Day 4 whole organism tp53 expression increased amount, abnormal
AB + MO1-mpi standard conditions Prim-5 whole organism tp53 expression increased amount, abnormal
Prim-5 whole organism Ab1-O-GlcNAc labeling increased amount, abnormal
AB + MO1-mpi chemical treatment: 6-diazo-5-oxo-L-norleucine Day 4 whole organism Ab1-O-GlcNAc labeling amount, ameliorated
AB + MO1-mpi chemical treatment: OSMI-1 Day 4 whole organism Ab2-ogt labeling amount, ameliorated
Day 4 whole organism tp53 expression amount, ameliorated
AB + MO1-mpi + MO1-ogt.1 control Day 4 whole organism Ab2-ogt labeling amount, ameliorated
AB + MO1-mpi + MO1-ogt.1 standard conditions Prim-5 whole organism tp53 expression amount, ameliorated
Prim-5 whole organism Ab1-O-GlcNAc labeling amount, ameliorated
Day 4 whole organism tp53 expression amount, ameliorated
Acknowledgments:
ZFIN wishes to thank the journal eLIFE for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Elife