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General Information
ZIRC
ZFIN ID: ZDB-FIG-170719-4
Alharthy et al., 2017 - Mechanistic evaluation of benzo[a]pyrene's developmental toxicities mediated by reduced Cyp19a1b activity. Toxicological sciences : an official journal of the Society of Toxicology   155(1):135-147 Full text @ Toxicol. Sci.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Conditions:
Knockdown Reagent:
Observed In:
Stage: Day 4

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
y1Tg chemical treatment by environment: benzo[a]pyrene Day 4 eye decreased size, abnormal
Day 4 pericardium edematous, abnormal
Day 4 swim bladder uninflated, abnormal
Day 4 whole organism decreased length, abnormal
Day 4 yolk edematous, abnormal
y1Tg chemical treatment by environment: benzo[a]pyrene, chemical treatment by environment: 17beta-estradiol Day 4 eye decreased size, abnormal
Day 4 pericardium edematous, ameliorated
Day 4 swim bladder uninflated, abnormal
Day 4 whole organism decreased length, abnormal
Day 4 yolk edematous, ameliorated
y1Tg chemical treatment by environment: 17beta-estradiol Day 4 eye decreased size, abnormal
Day 4 swim bladder uninflated, abnormal
Day 4 whole organism decreased length, abnormal
y1Tg chemical treatment by environment: Fadrozole hydrochloride Day 4 eye decreased size, abnormal
Day 4 pericardium edematous, abnormal
Day 4 swim bladder uninflated, abnormal
Day 4 whole organism decreased length, abnormal
Day 4 yolk edematous, abnormal
y1Tg chemical treatment by environment: Fadrozole hydrochloride, chemical treatment by environment: 17beta-estradiol Day 4 eye decreased size, abnormal
Day 4 pericardium edematous, ameliorated
Day 4 swim bladder inflated, ameliorated
Day 4 whole organism decreased length, ameliorated
Day 4 yolk edematous, ameliorated
y1Tg + MO3-cyp19a1b control Day 4 eye decreased size, abnormal
Day 4 pericardium edematous, abnormal
Day 4 swim bladder uninflated, abnormal
Day 4 whole organism decreased length, abnormal
Day 4 yolk edematous, abnormal
y1Tg + MO3-cyp19a1b chemical treatment by environment: 17beta-estradiol Day 4 eye decreased size, ameliorated
Day 4 pericardium edematous, ameliorated
Day 4 swim bladder uninflated, abnormal
Day 4 whole organism decreased length, ameliorated
Day 4 yolk edematous, ameliorated
Full text @ Toxicol. Sci.