header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-FIG-170718-11
Alharthy et al., 2017 - Mechanistic evaluation of benzo[a]pyrene's developmental toxicities mediated by reduced Cyp19a1b activity. Toxicological sciences : an official journal of the Society of Toxicology   155(1):135-147 Full text @ Toxicol. Sci.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Conditions:
Knockdown Reagent:
Observed In:
Stage Range: Long-pec to Day 4

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
y1Tg chemical treatment by environment: benzo[a]pyrene Long-pec hatching decreased occurrence, abnormal
y1Tg chemical treatment by environment: benzo[a]pyrene, chemical treatment by environment: 17beta-estradiol Long-pec hatching decreased occurrence, abnormal
Day 4 whole organism decreased life span, abnormal
y1Tg chemical treatment by environment: Fadrozole hydrochloride Long-pec hatching decreased occurrence, abnormal
Day 4 whole organism decreased life span, abnormal
y1Tg chemical treatment by environment: Fadrozole hydrochloride, chemical treatment by environment: 17beta-estradiol Long-pec hatching decreased occurrence, abnormal
Day 4 whole organism decreased life span, exacerbated
y1Tg + MO3-cyp19a1b control Long-pec hatching decreased occurrence, abnormal
Day 4 whole organism decreased life span, abnormal
y1Tg + MO3-cyp19a1b chemical treatment by environment: 17beta-estradiol Long-pec hatching occurrence, ameliorated
Day 4 whole organism decreased life span, ameliorated
Full text @ Toxicol. Sci.