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General Information
ZIRC
ZFIN ID: ZDB-FIG-170629-14
Costa et al., 2017 - Perturbations in cell signaling elicit early cardiac defects in mucopolysaccharidosis type II. Human molecular genetics   26(9):1643-1655 Full text @ Hum. Mol. Genet.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage Range: Day 4 to Days 14-20
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Day 4 to Days 14-20

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP el108Tg standard conditions Day 5 myocardium IFL
Days 14-20 atrial myocardium IFL
Days 14-20 atrioventricular canal IFL
Days 14-20 ventricular myocardium IFL
el108Tg + MO1-ids standard conditions Day 5 myocardium IFL
Days 14-20 myocardium IFL
ia18Tg standard conditions Day 4 heart IFL
ia18Tg + MO1-ids standard conditions Day 4 heart IFL
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
el108Tg + MO1-ids standard conditions Day 5 atrium increased size, abnormal
Day 5 myocardium increased thickness, abnormal
Days 14-20 cardiac ventricle heart trabecula formation disrupted, abnormal
Days 14-20 trabecular layer of the atrium absent, abnormal
ia18Tg + MO1-ids standard conditions Day 4 atrium increased size, abnormal
Full text @ Hum. Mol. Genet.