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Research
General Information
ZIRC
ZFIN ID: ZDB-FISH-170629-12
Fish name: el108Tg + MO1-ids
Genotype: el108Tg
Targeting Reagent: MO1-ids
HUMAN DISEASE MODELED by el108Tg + MO1-ids
Human Disease Conditions Citations
mucopolysaccharidosis II standard conditions Costa et al., 2017
GENE EXPRESSION
Gene expression in el108Tg + MO1-ids
RNA expression No data available
Protein expression No data available
PHENOTYPE
Phenotype in el108Tg + MO1-ids
Phenotype Conditions Figures
atrium increased size, abnormal standard conditions Fig. 4 from Costa et al., 2017
cardiac ventricle heart trabecula formation disrupted, abnormal standard conditions Fig. 4Fig. 5 from Costa et al., 2017
cardiac ventricle heart trabecula formation disrupted, ameliorated chemical treatment by environment: purmorphamine Fig. 5 from Costa et al., 2017
heart rudiment smoothened signaling pathway disrupted, abnormal standard conditions Fig. 5 from Costa et al., 2017
myocardium increased thickness, abnormal standard conditions Fig. 4 from Costa et al., 2017
smoothened signaling pathway decreased process quality, abnormal standard conditions Fig. 5 from Costa et al., 2017
trabecular layer of the atrium absent, abnormal standard conditions Fig. 4 from Costa et al., 2017
trabecular layer of ventricle decreased size, abnormal standard conditions Fig. 5 from Costa et al., 2017
trabecular layer of ventricle decreased size, ameliorated chemical treatment by environment: purmorphamine Fig. 5 from Costa et al., 2017

CITATIONS  (1)